Top 5 On Cycle Support 2025
Apr 10, 2025
Running a cycle? Then running support is non-negotiable. Without proper protection, your gains could come at the cost of your health. From liver strain and blood pressure spikes to joint stress and hormonal chaos, it’s not worth the gamble.
That’s where on-cycle support comes in. These supplements are built to defend your organs, balance your hormones, and reduce inflammation so you can push your performance without burning out your system.
Below are five of the most trusted, clinically-formulated support stacks on the market today. Let’s break down what they do and why they matter.
Blockade by Assault Labs is the ultimate on-cycle support formula, designed to defend your body from the harsh side effects of prohormone and anabolic cycles. Featuring a powerhouse lineup of ingredients like Milk Thistle, CoQ10, Alpha Lipoic Acid, and Turkey Tail Mushroom, Blockade delivers full-spectrum organ protection, joint support, blood pressure regulation, and antioxidant defense—all in one formula.
Instead of juggling multiple supplements, Blockade gives you a single, effective solution to safeguard your gains and your health.
Key Benefits:
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Full liver, heart, prostate, and kidney support
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Reduces inflammation and oxidative stress
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Helps manage blood pressure and joint strain
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Accelerates recovery and supports hormone balance
SHOP BLOCKADE ON CYCLE DEFENSE
Protex by Vital Alchemy is a complete on-cycle support solution designed to protect your body during intense training or prohormone use. With a targeted blend of clinically respected ingredients from both Chinese and European medicine, Protex delivers advanced liver detox, organ protection, and blood pressure support in one convenient formula.
Backed by ingredients like Milk Thistle, Alpha Lipoic Acid, Selenium, and Hawthorne Berry, Protex helps your body stay resilient and running clean—so you can focus on performance, not side effects.
Key Benefits:
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Comprehensive liver detox and regeneration
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Blood pressure and cardiovascular support
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Cholesterol regulation and antioxidant defense
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Ideal for stacking with any prohormone cycle
SHOP PROTEX CYCLE ASSIST & LIVER PROTECTION
Cycle Assist by Competitive Edge Labs is a fully dosed, all-in-one on-cycle and post-cycle support supplement built for serious athletes. With standardized herbal extracts and clinical doses of key ingredients, it offers comprehensive protection for your liver, heart, prostate, and blood pressure without unnecessary fillers.
From Milk Thistle and NAC for liver detox, to Hawthorne Berry and Celery Seed for cardiovascular health, Cycle Assist delivers high-potency support in a cost-effective package. Perfect for anyone running a prohormone or intense training cycle.
Key Benefits:
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Liver detox and regeneration
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Blood pressure and cholesterol support
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Prostate protection
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Antioxidant and cardiovascular health
Gear Support by Blackstone Labs is your go-to on-cycle defense formula, delivering full-spectrum protection while you focus on muscle growth. Designed for those running anabolic cycles, Gear Support helps safeguard your liver, heart, prostate, and blood pressure with a potent blend of 7 clinically-backed ingredients.
With essentials like Milk Thistle, NAC, and Saw Palmetto, it covers the basics—and then some. Don’t let side effects stall your gains. Keep your body protected and your cycle on track.
Key Benefits:
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Liver, prostate, and heart support
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Blood pressure and lipid management
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Antioxidant-rich formula for organ protection
Defend by Huge Supplements is your complete on-cycle support formula, built to protect vital organs, reduce inflammation, and keep you performing at your peak. With high doses of liver, cardiovascular, prostate, and hormonal support ingredients like Milk Thistle, NAC, TUDCA, and Red Clover, Defend helps your body stay strong through even the most intense cycles.
Key Benefits:
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Advanced liver and organ protection
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Supports hormonal and cardiovascular health
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Reduces oxidative stress and inflammation
