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4-Andro Information For Beginners & Advanced Users

What is 4-Andro?

4-Andro (4-androstene-3b-ol 17-one), also known as 4-Androsterone or 4-DHEA, is a naturally occurring DHEA isomer. Its become very popular as a legal bodybuilding prohormone and testosterone replacement alternative due to its high conversion rate to testosterone. 4-DHEA has been very helpful for users looking to increase muscle mass, strength, and overall performance.


What is the best 4-Andro Supplement?

Andro the Giant by Hard Rock Supplements

Andro The Giant is currently our highest rated 4-Andro supplement based on real user feedback and customer reviews. Most 4-Andro supplements only provide 50-65mg of 4-Andro per serving whereas Andro the Giant provides a generous 110 mg per each capsule. With 90 capsules per bottle, that's nearly 10,000 mg per bottle!

Andro The Giant


Top 4 Andro Products:

4-Androsterone Info | Shop Related Products

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Importance and Popularity of 4-Andro in Bodybuilding and Fitness

4-DHEA has become popular among bodybuilders, athletes, and fitness enthusiasts looking to maximize their gains because of its strong anabolic effects. It boosts testosterone levels and enhances lean tissue growth, making it a powerful part of workout routines and supplement plans.

The Goal of this Guide

This guide will give you a better understanding of the 4 Andro prohormone. We'll break down its science and benefits, along with practical information on dosage, cycling, and potential side effects. By the end, you should be well-prepared to decide if 4-DHEA is right for your fitness journey.

The Science Behind 4-Andro

Chemical Structure and Class

4-Andro is a synthetic prohormone that comes from dehydroepiandrosterone (DHEA), a hormone naturally found in the body. It belongs to the family of anabolic steroids in terms of structure. But as a prohormone, it's inactive until it turns into testosterone within the body.

Conversion of 4-Andro to Testosterone

When you take 4-Andro, enzymes in your liver change it into 4-androstenediol, which then becomes testosterone. This process increases overall testosterone levels in your body, leading to enhanced anabolic effects on muscle tissue and other benefits.

Different Types of 4-Andro Supplements

4-Andro supplements are available in various forms, with oral and cream/topical applications being the most common. Each form has its own unique advantages and drawbacks. Understanding the differences between them can help you choose the best option based on your goals and preferences.

4 Andro Oral Forms

Oral 4-Andro supplements come in various formats, such as capsules, tablets, and liquid solutions. These are ingested and absorbed through the digestive system, then broken down by the liver before entering the bloodstream.

  1. Convenience: Oral supplements are easy to take, require no preparation, and can be consumed quickly.
  2. Consistent dosage: With pre-measured capsules or tablets, you can be confident about the dosage you're consuming.
  1. Liver metabolism: Oral supplements are processed by the liver, which can potentially put stress on the liver and cause reduced absorption.
  2. Lower absorption: Some of the ingested supplement may be lost during digestion and metabolism, resulting in a lower effective dosage.
4 Andro Cream / Topical Forms

Topical 4-Andro supplements suspend the active ingredients within a gel or cream solution. They are applied directly to the skin, where they get absorbed through the epidermis and in turn enter the bloodstream. This bypasses the liver's first-pass metabolism, which can greatly increase absorption/delivery and reduce stress on the liver.

  1. Bypasses liver metabolism: Topical applications avoid the first-pass effect, reducing the potential for liver stress and increasing absorption.
  2. Direct absorption: Topical solutions are absorbed directly into the bloodstream through the skin barrier. This can potentially provide a faster or more efficient delivery of the active compound.
  1. Inconsistent absorption: Factors such as skin thickness, moisture levels, and individual responses can impact the absorption rate/effectiveness of topical applications.
  2. Potential skin irritation: Some individuals may experience skin irritation, redness, or other adverse reactions when using topical supplements.

When choosing between oral and topical 4-Andro supplements, consider your personal preferences, convenience, and pro's and con's of each form. It's essential to follow the suggested usage/instructions for proper application and dosage, regardless of the chosen form.

Mechanism of Action and Effects on Muscle Growth

The higher testosterone levels provided by 4-Andro help with protein synthesis and nitrogen retention in muscle cells. This leads to the growth of new muscle fibers, more muscle mass, and better strength.

Benefits of 4-Andro

Muscle Mass and Strength Gains

The main benefit of 4-Andro is its ability to increase muscle mass and strength. By boosting testosterone levels, it enhances anabolic processes, leading to better muscle growth, increased strength, and more effective workouts.

Enhanced Recovery and Reduced Muscle Soreness

4-Andro can also improve recovery and muscle soreness. Testosterone activates satellite cells, which help repair damaged muscle tissue. This results in less muscle soreness and faster recovery times, allowing for more intense and frequent training sessions.

Improved Libido and Sexual Function

As a testosterone precursor, 4-Andro can positively affect libido and sexual function. Testosterone plays a vital role in maintaining a healthy libido. The increased testosterone from 4-Andro use can lead to improved sexual performance and overall satisfaction.

Positive Effects on Mood and Well-Being

Testosterone has been linked to improved mood, higher energy levels, and a sense of well-being. By raising testosterone levels, 4-Andro can potentially lead to better mental health, increased motivation, and a greater sense of well-being.

4 Andro Dosing and Cycle Guidelines

Standard Suggested Dosage

4 Andro dosage can change based on factors like individual goals, experience, and tolerance. However, a typical starting point is 300-500 mg per day, divided into 3 doses spaced 5-6 hours apart. More experienced users may opt for higher doses, but it's essential to assess tolerance and carefully monitor for side effects.

Cycle Duration and Considerations

A typical 4-Andro cycle lasts 6-8 weeks. Each cycle should be followed by an equal amount of time off. This allows the body to properly recover and normalize hormone levels. It's crucial not to exceed this cycle duration to minimize the risks of side effects and long-term health consequences.

Stacking 4-Andro with Other Prohormones

4 Andro stacks well with other prohormones to enhance results further. Common stacks include 4-Andro with 1-Andro or Epiandrosterone. It's essential to research and understand the effects of prohormone stacks and adjust dosages accordingly to avoid potential side effects.

Post Cycle Therapy (PCT) Requirements

Post Cycle Therapy is a critical component of any prohormone cycle, including 4-Andro. PCT helps restore natural hormone production, prevent muscle loss, and minimize potential side effects. A standard PCT includes an over the counter supplement such as Post Cycle 3X. PCTs are ran for a period of 4-6 weeks, starting immediately after completion of your 4-Andro cycle.

Potential 4 Andro Side Effects and Risks

Estrogenic and Androgenic Side Effects

4-Andro may cause some estrogenic side effects due to its ability to aromatize to estrogen. These side effects can include water retention, gyno, and increased body fat.

Although 4-DHEA does not convert into DHT, Androgenic side effects can still occur. This includes side effects such as acne, hair loss, and increased body hair growth. The risks of these of side effects are generally far less common with 4-Andro compared to other DHT based prohormones.

Impact on Cholesterol Levels

4-Andro may negatively affect cholesterol levels, leading to an increase in LDL (bad) cholesterol and a decrease in HDL (good) cholesterol. This can raise concerns about cardiovascular health, particularly for those with pre-existing conditions or a family history of heart disease. Regular monitoring of cholesterol levels and maintaining a heart-healthy lifestyle is essential during any prohormone cycle.

Liver Toxicity Concerns

4-Andro is considered less liver-toxic than many other prohormones. However, there is still a risk of liver stress with prolonged use or excessive dosing. Its crucial to use liver support, limit your cycle duration, and follow proper PCT procedures to minimize any potential liver toxicity.

Suppression of Natural Testosterone Production

4-Andro can suppress the body's natural testosterone production. This can lead to hormonal imbalances and potential side effects such as testicular shrinkage and decreased sperm production. PCT is crucial for restoring natural hormone production and minimizing these risks.

Real-world Experiences and Reviews

Success Stories from Bodybuilders and Fitness Enthusiasts

Many bodybuilders and fitness enthusiasts have reported positive experiences when using 4-Andro. Users have cited noticeable gains in lean muscle mass, strength, and overall performance. They often share their success stories in forums, on social media, and within their fitness communities. Some users have even shared logs, documenting all the benefits of 4-Andro when used responsibly along with proper training and nutrition.

Andro the Giant itself has nearly 50 reviews posted by our customers who have used it and experienced the amazing benefits provided by 4-Andro. You can continue to read about Bulking in The Ultimate Guide to Properly Buling Article


Weighing the Pros and Cons of 4-Andro

Before deciding to use 4-Andro, it is essential to carefully consider the potential benefits and risks associated with its use. While it can offer significant muscle mass/strength gains, and improved recovery, it also carries potential side effects and health concerns. Proper cycle management, PCT, and lifestyle choices are crucial to maximize results and minimize risks.

If you are seeking to enhance muscle growth and performance, 4-Andro may be a suitable addition to your supplement regimen.

Tips for Maximizing Results and Minimizing Risks

To get the most out of 4-Andro, follow these tips:

  1. Stick to recommended dosages and cycle lengths.
  2. Implement a well-rounded training program and nutrition plan.
  3. Prioritize proper PCT and cycle management.
  4. Monitor your health, including regular check-ups and blood work.
  5. Avoid consuming foods or beverages high in calcium and iron. Don't consume any protein shakes within 2 hours of taking your doses of 4-DHEA in order to optimize delivery and absorption.

By following these guidelines, you can make the most of 4-Andro's potential benefits while minimizing its risks.


This content is for information and educational purposes only and is not intended as medical advice, diagnosis, or treatment. The statements made in this guide have not been evaluated by the Food and Drug Administration (FDA). The supplement mentioned in this guide, 4-Andro, is not intended to diagnose, treat, cure, or prevent any disease.

Always consult a qualified healthcare professional before starting any new supplement, diet, or exercise program. Avoid especially if you are pregnant, nursing, have a pre-existing medical condition, or are taking any medications. The information provided in this guide should not be used as a substitute for professional medical advice, diagnosis, or treatment. If you have any concerns or questions about your health, consult your healthcare provider.