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Phosphatidylserine Supplement: Unlock Your Brain’s Potential

Phosphatidylserine Supplement: Unlock Your Brain’s Potential

Posted by Leonard Shemtob on Jul 01, 2024

Wondering how phosphatidylserine can boost your brain health? This article covers its unique advantages, possible side effects, and proper dosage to help you make an informed decision. Learn how phosphatidylserine supports cognitive function and overall well-being.


Short Summary:

  • Phosphatidylserine is crucial for maintaining the structural integrity of brain cells and supporting cognitive function, particularly in older adults experiencing cognitive decline.
  • Phosphatidylserine supplements offer several advantages for users, including improved memory, mood regulation, and enhanced athletic performance, though they come with potential side effects such as headaches and digestive issues if taken in higher doses.
  • Individuals considering phosphatidylserine supplements should consult a healthcare provider, especially those who are pregnant, breastfeeding, on specific medication, or have certain medical conditions, due to possible interactions and safety concerns.
  • Buy the Best Phosphatidylserine Supplement and Unlock Your Mind and Body's Full Potential!


Understanding Phosphatidylserine

Illustration of phospholipid molecule structure

Phosphatidylserine (abbreviated as PS throughout this article) is a vital phospholipid that forms a crucial part of our cell membranes, including brain cell membranes and nerve cells. This fatty substance is integral to maintaining the structural integrity of cells, particularly in the brain. It ensures that brain cells remain protected and capable of efficient communication, which is essential for cognitive function and overall brain health.

Beyond its structural role, PS is deeply involved in regulating mood and sustaining cognitive capabilities such as attention, focus, processing speed, and memory. It’s fascinating to consider how something so microscopic impacts our daily lives at such a profound level. Additionally, it has been noted to enhance exercise performance, making it a multifaceted supplement.

However, the effectiveness of PS tends to decline with age, which can negatively impact memory and cognitive function, leading to age associated memory impairment. This natural decrease underscores the importance of considering PS supplementation, especially as we grow older, to help maintain mental acuity and overall brain health, keeping our memory sharp.


Benefits of Phosphatidylserine Supplementation

The positive effects of PS supplementation span across various aspects of health and well-being. One of the most significant advantages is its ability to protect brain cells and enhance communication between them, thereby supporting memory and cognitive function. Studies suggest that taking phosphatidylserine can lead to significant improvements in memory, which is particularly beneficial for older adults experiencing age-related cognitive decline.

In addition to memory complaints, PS plays an important role in mood regulation. It helps alleviate muscle soreness and has been suggested to improve mood and reduce hyperactive and impulsive behavior in children with ADHD. For instance, a study comparing PS to a placebo observed notable improvements in auditory memory, inattention, and impulsivity in children with ADHD.

Moreover, athletes have also found PS beneficial. This supplement can enhance exercise performance by reducing muscle soreness and protecting against increases in cortisol levels, a stress hormone that can impede athletic performance. Given these wide-ranging benefits, PS supplementation can be valuable for different groups of people aiming to boost their cognitive and physical performance.


Sources of Phosphatidylserine

Illustration of natural sources of phosphatidylserine

Phosphatidylserine is naturally present in various foods, particularly in:

  • Organ meats like chicken and beef liver, which are rich sources of this vital phospholipid
  • Soybeans, including edamame
  • Fatty fish such as mackerel and tuna

These foods contain significant amounts of phosphatidylserine.

For those who prefer not to consume organ meats or fish, PS supplements offer a convenient alternative. Many of these supplements are derived from plant sources, which are deemed safer and more accessible. Current supplemental sources include soy and cabbage, providing a plant-based option that avoids the potential risks associated with animal-derived products.

Sunflower lecithin is another excellent source for those with soy allergies. This plant-based option ensures that everyone can benefit from phosphatidylserine supplementation without the risk of allergic reactions.

Whether you choose to obtain phosphatidylserine through diet or supplements, there are ample sources to meet your needs.


Recommended Dosage for Phosphatidylserine

Illustration of recommended dosage for phosphatidylserine

Determining the proper dosage of phosphatidylserine depends on factors such as age and the specific purpose for supplementation. For adults, a typical dosage ranges from 100 to 200 mg daily. However, for more targeted outcomes like memory loss improvement, 100 mg taken two or three times per day is recommended.

Overall, PS is safe for short-term use, typically up to three months. However, adhering to recommended dosages and consulting with a healthcare provider will ensure the best outcomes while minimizing potential risks.


Potential Side Effects and Risks

While phosphatidylserine offers numerous advantages, it is essential to be aware of potential side effects and risks.

Common side effects can sometimes include:

  • headaches
  • stomach upset
  • insomnia
  • intestinal gas

These effects are more likely to occur at higher doses, particularly those exceeding 300 mg.

It’s also important to note that PS supplements are generally recognized as safe for up to three months of use. However, concerns about animal-sourced products transmitting diseases, such as mad cow disease, have led to a preference for plant-based supplements. Although no cases have been reported, choosing plant-derived phosphatidylserine can mitigate this risk.

Understanding these potential side effects and risks allows you to make informed decisions about phosphatidylserine supplementation, ensuring that you reap its full benefits while minimizing any adverse outcomes.


Top Phosphatidylserine Supplements

The Muscle Sculptor by Vital Alchemy

Muscle Sculptor by Vital Alchemy

Muscle Sculptor by Vital Alchemy is perfect for those looking to trim fat, build muscle, improve strength, and enhance the quality of their physique. Its powerful formula helps you achieve your fitness goals while supporting brain health.

Key Ingredients:

Key Advantages:

  • Enhances Muscle Growth: Supports muscle building and strength.
  • Boosts Memory: Improves cognition and memory.
  • Reduces Muscle Soreness: Aids in faster muscle recovery.
  • Stress Management: Encourages a relaxed and peaceful mindset.
  • Fat Loss: Ingredients like Grains of Paradise and Cayenne Pepper support fat loss.
  • Diuretic Effect: Helps reduce water retention with Dandelion Extract and Juniper Berry.

Abliderate Ammo by EvoMuse

Abliderate Ammo by EvoMuse

Abliderate Ammo by EvoMuse is designed to help you achieve peak performance. With its unique blend of Phosphatidylserine along with other ingredients, it enhances muscle growth, boosts cognitive function, improves workout performance, and supports fat loss.

Active Ingredients:

  • Phosphatidylserine (PS)
  • Euphorbia Kansui Triterpenes
  • Cyclodextrin-Emodin Complex
  • Momordica Charantia Extract
  • Galangin
  • Magnolia-HPBCD Complex
  • Vitamin C
  • Zinc Gluconate

Key Advantages:

  • Boosts Memory: Enhances recall and cognitive function.
  • Enhances Focus: Helps improve attention, mental clarity, and focus during workouts.
  • Decrease Muscle Soreness: Aids in faster recovery post-exercise.
  • Stress Reduction: Helps lower cortisol, the body's primary stress hormone.
  • Supports Immune Function: With Vitamin C and Zinc for immune health.
  • Antioxidant Properties: Provides antioxidant support to reduce oxidative stress.
  • Fat Loss: Ingredients help to enhance metabolism and promote fat burning.
Read More About Abliderate Ammo:

EvoMuse Supplements: Elevating Your Fitness Journey to New Heights


Ab-Solved by Xtreme Performance Gels

Ab-Solved by Xtreme Performance Gels

Ab-Solved by Xtreme Performance Gels is your go-to for cutting-edge performance enhancement. This supplement is packed with phosphatidylserine to help you push your limits and achieve your fitness goals, including supporting fat loss.

Key Ingredients:

  • Phosphatidylserine (PS)
  • Pomegranate Seed Oil
  • D-limonene
  • Lecithin
  • Triglyceride Complex
  • 7-OXO-DHEA
  • Trans-Resveratrol

Key Advantages:

  • Improves Your Performance: Enhances endurance and strength.
  • Supports Brain Health: Promotes cognition and focus.
  • Reduces Muscle Fatigue: Helps in quicker recovery times.
  • Stress Alleviation: Supports a calmer and more balanced emotional state.
  • Anti-Inflammatory: Contains pomegranate seed oil to help reduce inflammation.
  • Hormonal Balance: Supports hormone regulation with 7-OXO-DHEA.
  • Fat Loss: Ingredients help boost metabolism and enhance fat burning.

Inhuman Pre-Workout by AfterDark

Inhuman Pre Workout by AfterDark

Inhuman Pre Workout by AfterDark is your ultimate pre-workout supplement. Packed with phosphatidylserine (PS), it enhances your strength, workout performance, fat loss, increases energy, and supports brain health.

Key Ingredients:

  • CognatiQ (blend of natural ingredients including pterostilbene & phosphatidylserine)
  • Vitamin B3, B3, B12
  • Caffeine Anhydrous
  • Dicaffeine Malate
  • Micro Encapsulated Caffeine
  • Theobromine HCl
  • Alpha Yohimbine
  • L-Citrulline
  • L-Taurine
  • Glycogen Polymers (Dextrose, D-Ribose)
  • L-Tyrosine
  • L-Theanine
  • Huperzine A
  • Beta Alanine
  • Creatine Pyrinox

Key Advantages:

  • Boosts Athletic Performance: Enhances strength and endurance.
  • Improves Focus: Increases mental clarity and focus during workouts.
  • Reduces Muscle Fatigue: Helps in quicker recovery.
  • Energy Boost: Multiple forms of caffeine provide sustained energy.
  • Improves Blood Flow: Ingredients like L-Citrulline enhance nitric oxide production.
Related Read:

Unleash Your Inner Beast with Inhuman Pre-workout: A Comprehensive Review


Pride Pre-Workout by EHPLabs

Pride Pre-Workout by EHPLabs

Pride Pre-Workout by EHPLabs is formulated to help you dominate your workouts. With phosphatidylserine and other powerful ingredients, it boosts your performance in the gym, helps build more muscle, recover faster, and support cognition.

Key Ingredients:

  • SerinAid (Phosphatidylserine / PS)
  • L-Citrulline
  • Nitrosigine
  • BCAAs
  • EAAs
  • Caffeine Anhydrous
  • Infinergy (Di-Caffeine Malate)
  • Green Coffee Extract
  • Innova Tea
  • Yerba Mate
  • L-Tyrosine
  • Taurine
  • Theobromine

Key Advantages:

  • Enhances Performance & Exercise Capacity: Boosts strength, endurance, and energy.
  • Supports A Healthy Brain: Promotes cognitive abilities and focus.
  • Reduces Muscle Soreness: Aids in faster recovery.
  • Sustained Energy: Multiple sources of caffeine for lasting energy.
  • Improves Muscle Recovery: BCAAs and EAAs support muscle repair and growth.
Related Article:

Pride Pre Workout Review: The King of Pre Workouts


Clinical Research and Evidence

Clinical research on phosphatidylserine supplements highlights multiple health advantages, although many studies are small and dated. For example, a study combining phosphatidylserine and omega-3 fatty acids showed significant improvements in mood and reductions in hyperactive behavior among children with ADHD compared to a placebo.

Athletes, in particular, may benefit from phosphatidylserine’s ability to boost performance and increase exercise capacity. Studies have shown that it helps relieve performance anxiety by balancing cortisol levels and other hormones in the brain. Additionally, PS can speed up recovery and prevent muscle soreness, enhancing overall well-being and concentration in athletes.

Despite these promising findings, more research is needed to confirm the effectiveness of phosphatidylserine, including conducting a clinical trial. Ensuring robust, larger-scale studies will provide clearer insights into its potential benefits and applications across different populations.


Who Should Avoid Phosphatidylserine?

Certain groups should avoid taking phosphatidylserine due to potential downsides and interactions. Pregnant and breastfeeding women should steer clear of this supplement due to insufficient reliable information regarding its safety for these groups. Similarly, children should not use PS supplements as their safety is not well established for this age group.

Individuals with specific medical conditions or those taking certain medications should also exercise caution. This includes people on:

  • blood thinners
  • antidepressants
  • antihistamines
  • medications for glaucoma or Alzheimer’s disease

due to potential interactions. Additionally, it’s advisable to avoid phosphatidylserine within two weeks of scheduled surgery because of its potential blood-thinning effects.


How to Choose a Quality Phosphatidylserine Supplement

Illustration of quality phosphatidylserine supplement selection

Choosing a quality phosphatidylserine supplement involves several key considerations. Opting for supplements made from plant sources is advisable to avoid the risk of animal disease transmission, such as bovine cortex derived products. Additionally, ensuring that the supplement has been tested for purity by third-party bodies can confirm the accuracy of the ingredients listed on the label.

Another important aspect is selecting non-GMO and allergen-free options, especially if you have specific dietary restrictions or allergies. Supplements that combine phosphatidylserine with other nutrients like vitamins and minerals can also enhance effectiveness, making them an essential component in your daily nutrition and regimen.

Finally, balancing cost with quality is crucial. While prices may vary, choosing a supplement that offers the right concentration of phosphatidylserine for the desired effect is essential. By considering these factors, you can select a supplement that meets your needs and ensures the best possible outcomes.


Maintaining Cognitive Health

Illustration of maintaining cognitive health

Maintaining cognitive health requires a multifaceted approach. Regular physical activity is linked to the improved health of your brain and can lower the risk of developing Alzheimer’s by increasing brain glucose metabolism. Additionally, maintaining cardiovascular health through a balanced diet and controlling high blood pressure can protect both the brain and the heart.

Proper sleep, typically seven to nine hours per night, is crucial for cognitive function. Managing chronic health conditions such as diabetes and high cholesterol is also essential. Limiting alcohol use and avoiding smoking can further benefit cognitive health.

Engaging in cognitive training exercises and social activities can help maintain cognitive health in older adults, as well as support other cognitive functions. Participation in community programs and preventing falls and treating age-related sensory conditions can reduce the risk of brain injuries that impact cognitive health. By adopting these practices, you can support the health of your mind and cognitive abilities throughout life.


To Wrap Things Up

Phosphatidylserine is an essential component of brain cell membranes, playing a critical role in memory, your emotional state, and cognitive function. While its benefits are impressive, it’s crucial to consider potential side effects and interactions with other medications.

Consulting a healthcare provider ensures safe and effective use, allowing you to harness the full potential of phosphatidylserine supplementation. Embark on your journey to improved cognitive health and explore the benefits of phosphatidylserine today.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider before starting any new supplement regimen, especially if you have any pre-existing medical conditions or are taking other medications.

Written and Sponsored by Leonard Shemtob

Leonard Shemtob is President of Strong Supplements. Leonard has been in the supplement space for over 20 years, specializing in fitness supplements and nutrition. Leonard appears on many podcasts, written over 100 articles about supplements and has studied nutrition, supplementation and bodybuilding. 

Leonard's articles have been published in many top publications around the web. Leonard enjoys weight training, playing basketball and yoga, and also enjoys hiking. In his free time he studies and works on improving himself. For more detailed information, visit his official blog.

Phosphatidylserine FAQs

Phosphatidylserine is a phospholipid essential for cell membranes, particularly in the brain, and is important for cognitive functions and mood regulation.
Taking phosphatidylserine supplements can lead to improved memory, cognitive function, regulation of your mental state, reduced ADHD symptoms, and enhanced workout performance.
Natural sources of phosphatidylserine include organ meats like chicken and beef liver, soybeans, and fatty fish such as mackerel and tuna. Incorporating these foods into your diet can help increase your phosphatidylserine intake.
Potential side effects of phosphatidylserine may include headaches, stomach upset, insomnia, and intestinal gas, especially at higher doses. Be sure to monitor your symptoms and consult a healthcare professional if you experience any adverse effects.
Phosphatidylserine should be avoided by pregnant and breastfeeding women, children, and individuals with certain medical conditions or taking specific medications due to potential concerns and interactions.

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