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​Best Supplements for Muscle Growth

​Best Supplements for Muscle Growth

Posted by Leonard Shemtob on May 07, 2024

Sculpting an impressive physique requires dedication in the gym, but what you fuel your body with outside of those intense workouts is equally important. While a balanced diet is crucial, many fitness enthusiasts turn to targeted supplements to maximize their muscle growth potential. 

But with a sea of options on the market, which ones truly deliver? In this article, we'll explore a range of supplements that have been scientifically proven to support muscle growth.

Whether you're a seasoned gym-goer or just starting your fitness journey, understanding the best supplements for muscle growth can make a significant difference in your results. 

So, let's dive in and uncover the top picks that can help you maximize your gains and unlock your true potential!

[Related Article] Muscle Building Supplements - The Ultimate Resource

Short Summary

  • Introduction to the Best Supplements for Muscle Growth: Get an overview of the role of supplements in muscle growth and fitness enhancement.
  • Benefits of Muscle Building Supplements: Explore the advantages these supplements offer for boosting muscle growth and recovery.
  • Key Ingredients to Look For: Discover the essential ingredients commonly found in effective muscle-building supplements.
  • Buying Guide for Muscle-Building Supplements: Gain insights into factors to consider when purchasing muscle-building supplements, ensuring you make informed decisions.
  • Ready to begin your fitness journey? Get the perfect muscle-building supplement, AnaFuse by Vital Alchemy, to support you every step of the way.

Best Supplements for Muscle Growth Reviewed

  1. AnaFuse by Vital Alchemy: Best Overall
  2. Colossal Muscle by Hard Rock Supplements: Best for Increasing Lean Muscle Mass + Protein Synthesis and Overall Performance.
  3. AlphaBulk by Olympus Labs: Best For Muscle Building + Strength
  4. AlphaBuild by Olympus Labs: Best Muscle Builder + Cutting Agent
  5. AlphaDefy by Olympus Labs: Best Supplement for Muscle Growth + Metabolic Support and Overall Health

1- AnaFuse by Vital Alchemy

AnaFuse by Vital Alchemy

Introducing Anafuse by Vital Alchemy – the pioneering Dual Agent Bulking Stack engineered to not only help you build muscle but also maintain it! This supplement integrates a blend of recently discovered anabolics to enhance muscle-building synergy without the risk of adverse effects.

Packed with natural ingredients like Epicatechin, Ajuga Turkestanica, HICA, Eriobotrya Japonica, Vitamin D3, and more, Anafuse is a potent mass-gain product ideal for post-workout recovery and athlete performance.

It accelerates muscle recovery, enhances endurance, promotes mass gain, and boosts protein synthesis, all while harnessing the power of an all-natural formula. 

Anafuse supports muscle recovery, endurance, and natural mass gain with its all-natural formula, providing a comprehensive solution for individuals seeking to add lean muscle mass to their physique.

Key Ingredients of AnaFuse by Vital Alchemy

Epicatechin: Derived from plants like green tea and cocoa, Epicatechin is a potent antioxidant known for its ability to reduce Myostatin levels. 

Myostatin, a natural growth factor protein in the body, regulates and limits muscle growth according to genetic predisposition. This ingredient helps reduce this protein and promotes muscle development beyond genetic potential.

Ajuga Turkestanica: Also known as Turkesterone, this Uzbekistan-native plant extract is rich in ecdysteroids. Turkesterone is renowned for its multifaceted benefits, including fat loss, muscle building, improved focus, and enhanced muscle recovery. It has been traditionally used in Eastern medicine to address various health issues such as digestion and cardiovascular problems.

HICA (Alpha-Hydroxyisocaproic Acid): As a metabolite of the amino acid leucine, HICA plays a crucial role in increasing muscle protein synthesis and reducing muscle protein breakdown.

Eriobotrya Japonica: Derived from the Eriobotrya Japonica (EJ) plant, this ingredient boasts a range of natural anabolic compounds beneficial for muscle building, fat burning, and enhancing athletic performance. Its key chemical constituents, include Epicatechin, Ursolic Acid, Tormenic Acid, and Ellagic Acid. 

Studies suggest that Eriobotrya Japonica also prevents muscle atrophy and promotes muscle hypertrophy, making it particularly beneficial for preserving muscle mass during caloric deficits.

Vitamin D3: Crucial for muscle health, Vitamin D3 deficiency can lead to decreased protein synthesis, reduced strength, weakness, and muscle wasting. 

Additionally, inadequate levels of Vitamin D3 may result in fatty muscles, negatively impacting strength and power.

Quercetin: This flavanol, commonly found in fruits, vegetables, leaves, and grains, is known for its support of respiratory health, cardiovascular health, and balanced blood pressure. 

In the context of Epicatechin, Quercetin plays a significant role by inhibiting the enzyme class known as "sulfotransferases" from binding to Epicatechin and attaching a sulfur atom to it, thus preventing its deactivation.

Key Benefits of AnaFuse by Vital Alchemy

  • It improves mass gains.
  • It helps reduce body fat.
  • It boosts muscle endurance.
  • It helps increase muscle hardness.
  • It increases strength.
  • It enhances your muscle pumps.
  • It speeds up your muscle recovery.
  • It helps reduce muscle soreness.
  • It helps increase protein synthesis.

Customer Reviews: AnaFuse by Vital Alchemy

 Excellent product

"I have been taking this for a week now and have already seen an increase in size without any water weight. My workouts have been more intense as i am finding it harder to wear myself out."

-Brandon A.

 Great results

"This product produces excellent results, that you’ll quickly notice within weeks. My focus and strength are doubled while I’m on this product!"

-Micah H.


"Increased strength, fat loss and *********** gain. All in one. Very good product that I would recommend"


2- Colossal Muscle by Hard Rock Supplements

Colossal Muscle by Hard Rock Supplements

Introducing Colossal Muscle by Rock Hard Supplements, featuring two potent ingredients. One of these ingredients has been studied for 10 weeks, demonstrating notable improvements in muscle mass and strength. 

Colossal Muscle uniquely combines these ingredients in doses not found elsewhere. This formula aims to support muscle building, strength enhancement, endurance improvement, and protein synthesis.

Key Ingredients of Colossal Muscle by Hard Rock Supplements

20-Hydroxyecdysone (Ecdysterone): This plant-derived compound has been studied for its potential muscle-building effects. 

A 2019 study ("Ecdysteroids as Non-Conventional Anabolic Agent Study") showed some participants experienced increased muscle mass and strength after 10 weeks.

Uzbekistan Ajuga Turkestanica (Turkesterone): Uzbekistan Ajuga Turkestanica, commonly known as Turkesterone, is a natural ecdysterone present in various plant and animal species. 

Renowned for its potential benefits in fat loss, muscle building, focus enhancement, and muscle recovery, Turkesterone is a key component in traditional Eastern medicine. Turkesterone has historical usage in traditional Eastern medicine for treating digestive and cardiovascular health.

Key Benefits of Colossal Muscle by Hard Rock Supplements

  • It helps build muscle.
  • It enhances protein synthesis.
  • It prevents muscle breakdown.
  • It improves endurance.
  • It helps increase strength and power.
  • It boosts muscle mass.
  • It improves fat loss.
  • It enhances your focus.
  • It supports your overall performance.

Customer Reviews: Colossal Muscle by Hard Rock Supplements

 On second bottle

"First bottle was great - took a little to see the resutlts but then they hit and you are like yes im loving it! just started my second bottle - thanks!"



"This hard rock product is awesome.

My strength increased rapidly and extreme pumps during the sessions. ********** muscle gain!"


 Colossal muscle

"Was definitely a little weary about this product being new to the market. I gave it a try and it took about 3 weeks but results started coming. I bought 2 bottles so very interested to see how the second bottle works. Will come back in 30 more days to give a follow up."


3- AlphaBulk by Olympus Labs

AlphaBulk by Olympus Labs

Introducing ALPHABULK by Olympus Labs, a cutting-edge addition to the muscle bulking supplement arena. This product is tailored for individuals seeking substantial gains in muscle mass and strength without compromising on effectiveness.

ALPHABULK features α-Cedrene, an innovative anabolic agent known for its remarkable ability to enhance skeletal muscle mass and strength while aiding in fat loss. Complementing this is α-Ionone, now in its potent liquid form, further increasing muscle protein synthesis and serving as a potent anti-catabolic and lipotropic agent.

What sets ALPHABULK apart is its utilization of Liquigel capsules, a pioneering technology ensuring maximum absorption for optimal results. This delivery system ensures you get the maximum benefits.

Additionally, ALPHABULK incorporates PhytoFUSE Tectochrysin, also known as 5-hydroxy-7-methoxyflavone, renowned for its exceptional oral bioavailability and clinical efficacy. This unique ingredient promotes protein synthesis, skeletal muscle hypertrophy, enhanced ATP production, and aids in endurance and recovery.

Key Ingredients of AlphaBulk by Olympus Labs

Tectochrysin PhytoFUSE 150 mg: Derived from Black Ginger roots, Tectochrysin serves as a foundational element utilized by the body to stimulate its own benefits. Studies on Methoxy Flavones in Black Ginger highlight Tectochrysin's potency in promoting skeletal muscle hypertrophy, leading to increased Myotube diameter. 

Its benefits extend to enhancing protein synthesis, nitrogen retention, muscle endurance, recovery, and lean muscle mass by fostering skeletal muscle hypertrophy.

Urolithin B (100 mg): Urolithin B is one of the four metabolites of ellagic acid and ellagitannins. Research has indicated that supplementing the diet with ellagitannins can mitigate muscle damage experienced during intense exercise and protect muscles against stresses induced by a high-fat diet. 

Clinical studies on Urolithin B in mice have revealed its ability to enhance myotube growth and differentiation by increasing protein synthesis.

α-Cedrene 70% 1500 mg: ALPHABULK incorporates a high dosage of highly purified, isolated α-Cedrene, renowned for its unique effects compared to other actives found in cedarwood. Recent research indicates α-Cedrene as a promising agent for enhancing skeletal muscle mass and strength.

α-Ionone 80% (200 mg): Ionones, including α-ionone, are part of the rose ketone family and can be found in various essential oils and fruits. ALPHABULK incorporates a clinically validated dosage of highly purified, isolated α-ionone, which has been shown to be a potent stimulator of myogenesis (muscle formation) and a potent anti-atrophic agent for skeletal muscle.

Key Benefits of AlphaBulk by Olympus Labs

  • It helps increase muscle protein synthesis.
  • It enhances anabolic signaling.
  • It boosts lean muscle growth.
  • It improves your strength.
  • It helps increase muscle mass.
  • It increases fat oxidation.
  • It helps increase lipolysis.
  • It supports overall exercise performance and recovery.

Customer Reviews: AlphaBulk by Olympus Labs

 Alpha Bulk

"I recently purchased Alpha Bulk two weeks ago and all I can say is WOW!!!! The only up downside about the pills are the taste, I’m taking 3 pills daily on an empty stomach. I like to train that way. They give me more endurance and can get out an extra rep or two before failure. No size yet, I’m only two weeks in. I ordered 2 bottles to run so I’m hoping to get a bit vascular full size."

-LaMichael W.

 Quality supplement

"I’m using this a in my pct and it’s been 3 weeks and I haven’t lost any weight."


 Stellar Pumps and Vascularity!

"About 3 weeks in and man the pumps in the gym are incredible. Feel like Alphabulk really is starting to bring out my physique. Noticing it feels better when I am in a caloric surplus. Also I am just now seeing the strength increases. Each week the weight and reps are going up on my bench and squat. Excited to see how 8 weeks treats me."

-Tony H.

4- AlphaBuild by Olympus Labs

AlphaBuild by Olympus Labs

Introducing AlphaBuild, the latest addition to Olympus Labs' premium product line. This innovative supplement has been designed to enhance muscle-building potential by targeting key signaling molecules. Additionally, it aims to amplify the body's ability to burn fat through a multifaceted approach.

AlphaBuild is a comprehensive formula engineered to target fat loss and enhance muscle growth through a variety of innovative pathways. 

This includes inhibiting the muscle-limiting factor Myostatin, boosting mitochondrial biogenesis and output, improving energy production and exercise performance, enhancing insulin sensitivity, and amplifying the key anabolic/thermogenic signaling molecule, Cyclic-Adenosine Monophosphate (cAMP).

Key Ingredients of AlphaBuild by Olympus Labs

α-Ionone: A member of the rose ketones compound family, Ionones are aromatic compounds found in trace amounts in various essential oils and fruits like raspberries. They come in three forms: alpha, beta, and gamma. 

Due to their strong aroma, Ionones are commonly used in fragrances, cosmetics, and food flavoring additives. AlphaBuild incorporates a substantial clinical dose of purified α-ionone, known for its unique and promising role. 

Recent studies highlight α-ionone as a powerful stimulator of myogenesis and a protective agent against skeletal muscle atrophy. These pathways play a crucial role in promoting muscle growth and minimizing muscle breakdown simultaneously.

Abscisic Acid: Abscisic Acid is a naturally occurring isoprenoid compound initially discovered in plants during the 1960s. As a significant phytohormone, it plays an essential role in regulating various aspects of plant growth, development, and responses to stress. 

In humans and rats, Abscisic Acid has demonstrated potent glucose disposal properties, leading to improved glucose tolerance and reduced insulin levels through an insulin-sparing mechanism. 

It enhances muscle glucose uptake by boosting AMP-K and GLUT-4 expression, ultimately enhancing muscle glycogen content.

Chromium Picolinate: Chromium Picolinate is an essential mineral known for its role in regulating insulin levels in the body. It functions through a protein called Chromodulin, which enhances insulin receptor signaling.

Key Benefits of AlphaBuild by Olympus Labs

  • It enhances ATP production.
  • It helps boost muscle protein synthesis.
  • It improves vascularity.
  • It increases anabolic signaling.
  • It improves lean muscle growth.
  • It improves insulin sensitivity.
  • It increases lipolysis and fat oxidation.
  • It supports your overall performance.
  • It helps increase your strength.
  • It accelerates your muscle recovery.

Customer Reviews: AlphaBuild by Olympus Labs

 Alpha build

"Been using for little over a week seem to be working as advertised so fa far very happy with this supplement"

-Al P.

 Loving it so far..

"I started it last Saturday. Did chest yesterday. Massive pump. Enjoying so far, full review coming soon."

-Josh S.

 A truly great product

"One of the best aspects of this supplement is the pump/fullness you feel almost constantly. Even without a pre workout this stands well on its own. Still have around two weeks left and I’m down 3.5 pounds with strength still increasing. If you’re hesitant on buying it just pull the trigger and do it, it’s worth it."

-Matthew B.

5- AlphaDefy by Olympus Labs

AlphaDefy by Olympus Labs

Introducing AlphaDefy: the game-changing supplement formulated to shatter your physical limitations and unleash genetic potential. It helps you achieve enhanced muscle growth, fat loss, and improved athletic performance.

The formula is designed to activate multiple PPAR pathways, which play crucial roles in metabolism and muscle development. 

By targeting these key pathways, the supplement seeks to provide users with the means to surpass their current physical boundaries and attain their desired body composition goals.

Key Ingredients of AlphaDefy by Olympus Labs

Garcinia Mangostana L. (peel) Extract (1500mg): Extracted from the peel of the mangosteen fruit, this ingredient is rich in xanthones like α-mangostin and γ-mangostin, known for their antioxidant properties and support for lipid metabolism and energy utilization.

MitoBurn™ (L-β-Aminoisobutyric Acid) (500mg): MitoBurn™ is a form of L-β-Aminoisobutyric Acid. It's believed to help convert white adipose tissue into brown adipose tissue, potentially boosting thermogenesis and fat oxidation. It's often likened to an exercise mimetic for its ability to mimic some benefits of exercise at the cellular level.

Artemisia Iwayomogi Extract (300mg): This extract, standardized for dibromo-4-methoxybiphenyl, is derived from a plant used in Korean medicine. It may activate PPAR-Delta, a regulator of lipid metabolism, supporting increased fat burning and endurance.

Genistein (50mg): Genistein is a powerful isoflavone known for its potential to activate PPAR-Beta, which could enhance fatty acid oxidation and muscle growth.

Selective Fat Ignition System (25mg): This blend includes Inulin, Chromium Picolinate as Chromax®, and Avocado (Persea americana) extract. Chromium Picolinate enhances insulin sensitivity, while Avocado extract, standardized to Abscisic Acid, may aid in glucose management and possess anti-inflammatory properties. Inulin, a fiber, promotes digestive health and may indirectly support weight management.

Key Benefits of AlphaDefy by Olympus Labs

  • It suppports your overall metabolic health.
  • It reduce inflammation and oxidative stress.
  • It helps increase energy and endurance.
  • It increases fat loss and muscle regeneration.
  • It increases insuline sensitivity.
  • It increases your thermogensis.
  • It boots overall muscle performance.
  • It improves your overall health and well ness.

Customer Reviews: AlphaDefy by Olympus Labs

 Impressive results added to my stack

"I added this to the dad *** transformation stack and dropped another 7 lbs in about 10 days on my cut. Also starting to see some definition too."

-Joseph S.

 Increasing in the right areas - beta tester

"Muscle preservation in a caloric deficit was the most notable effect for me, personally. Everything tightened up, vascularity increased, and nutrients were shuttled right where they needed to be."

-Owen Z.

 Works great -beta tester

"It works as stated. My strength as increased and recovery has been good. All of this while training fasted. It has also helped with nutrient partitioning. My diet hasn’t been the best and I’ve still been able to recomp nicely."

-Marty K.

How to Build Muscle Naturally

Building muscle naturally means using your body's own abilities to grow stronger and bigger. Here are some simple ways to do it:

Eat Right: Your body needs the right nutrients to build muscle. Eat plenty of protein, like chicken, fish, eggs, and beans. Also, make sure to get enough carbohydrates for energy and healthy fats for overall health.

Strength Training: Strength training is vital for building muscle naturally. Engage in exercises that challenge your muscles, such as weightlifting or bodyweight workouts like push-ups, squats, and lunges. Begin with lighter weights or resistance and progressively increase as you become stronger.

Rest and Recovery: Ensuring adequate rest is crucial for muscle development. Prioritize sufficient sleep each night to facilitate muscle repair and growth. Additionally, incorporating rest days into your routine helps prevent injuries and allows muscles to recuperate effectively.

Maintain Hydration: It's important to stay hydrated for muscle growth and overall well-being. Aim to drink enough water throughout the day, especially when you're active or sweating a lot.

Consistency: Achieving muscle growth requires dedication and persistence. Stick to your workout and dietary plans consistently. Set achievable goals, monitor your progress, and acknowledge your milestones as you advance.

How to Choose the Best Supplement for Muscle Growth

When it comes to selecting the right supplement for muscle growth, it's important to make informed choices. 

Here are some straightforward tips to help you choose the best supplement for your needs:

Research Ingredients: Look for supplements with scientifically-backed ingredients known to support muscle growth, such as protein supplements, creatine supplements, branched-chain amino acids (BCAAs).

Read Reviews: Take the time to read reviews from other users to see what they have to say about the supplement. Look for reviews from people who have similar fitness goals and lifestyles as you.

Consider Your Goals: Choose a supplement that aligns with your specific fitness goals and needs.

Consider Your Budget: Supplements can vary widely in price, so consider how much you're willing to spend.

Look for Third-Party Testing: Choose supplements that have been tested by third-party organizations for quality and safety. This ensures that you're getting a product that meets high standards of purity and potency.

Consult a Professional: If you're unsure about which supplement to choose, consider consulting a healthcare provider, nutritionist, or fitness expert for personalized recommendations based on your individual needs and health status.

FAQs: Best Supplements for Muscle Growth

Q: Can I build muscle without supplements?

A: Absolutely! A balanced diet with sufficient protein, consistent strength training, and proper rest are the cornerstones of muscle building. Supplements may play a supporting role, but they are not a replacement for these core elements.

Q: Are there any side effects from muscle-building supplements?

A: Some dietary supplements may have mild side effects. Always check the label, consult your doctor before starting any new supplement, especially if you have any health conditions.

Q: What is the best time to take muscle-building supplements?

A: The timing of supplements depends on the specific product and its ingredients.

Q: Can muscle-building supplements help me lose body weight?

A: While some supplements may indirectly support weight management, building muscle itself can help boost metabolism.

Q: Are muscle growth supplements safe to use?

A: Generally, muscle growth supplements are safe when used as directed. However, it's essential to choose high-quality supplements from reputable brands and follow the recommended dosage instructions.


In conclusion, building muscle naturally involves a holistic approach that encompasses proper nutrition, effective training, rest, and supplementation. 

By focusing on a balanced diet high in protein, healthy fats, and carbohydrates, and prioritizing rest and recovery, individuals can enhance their muscle growth and overall fitness.

Additionally, including high-quality supplements can offer added support for muscle development. Remember, patience and consistency are key when it comes to reaching long-term muscle growth goals. 

By adopting these strategies and staying committed to your fitness journey, you can unlock your body's full potential and achieve the strong, healthy physique you desire.


Written and Sponsored by Leonard Shemtob

Leonard Shemtob is President of Strong Supplements. Leonard has been in the supplement space for over 20 years, specializing in fitness supplements and nutrition. Leonard appears on many podcasts, written over 100 articles about supplements and has studied nutrition, supplementation and bodybuilding. 

Leonard's articles have been published in many top publications around the web. Leonard enjoys weight training, playing basketball and yoga, and also enjoys hiking. In his free time he studies and works on improving himself. For more detailed information, visit his official blog.