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​5 Best Nootropic Pre-Workout Supplements

​5 Best Nootropic Pre-Workout Supplements

Posted by Leonard Shemtob on Oct 19, 2023

5 Best Nootropic Pre-Workout Supplements

Have you ever felt like you needed an extra mental and physical boost before hitting the gym or engaging in your workout routine? If so, you're not alone. Many fitness enthusiasts and athletes are turning to nootropic pre-workout supplements to help sharpen their focus, enhance their cognitive function, and improve their physical performance.

In this article, we'll explore the 5 best nootropic pre-workout supplements that can help you boost your brainpower and optimize your workouts. We'll explore what makes these supplements stand out in the crowded fitness market and why they're gaining popularity among fitness enthusiasts.

Whether you are an experienced athlete looking for an extra edge or someone relatively new to the fitness scene, this article is your guide to the top 5 nootropic pre-workout supplements. Get ready to discover how these innovative formulas can help you reach new heights in your fitness journey and take your workouts to a whole new level.

Short Summary

Nootropic Pre-Workouts Explained: Discover the concept of nootropic pre-workout supplements, which combine cognitive enhancers with traditional pre-workout ingredients to boost both mental focus and physical performance.

The Top 5 Nootropic Pre-Workouts: Explore our list of the best five nootropic pre-workout supplements, each with its unique blend of ingredients created to maximize your potential at the gym.

Sharpening Your Mind and Strengthening Your Body: Understand how these cutting-edge formulas can help you achieve enhanced focus, motivation, and energy, all while supporting your physical strength and endurance.

Ready to Start Your Journey?: Begin your enhanced workout journey by trying our top recommended nootropic pre-workout: Wild Thing by Assault Labs.

Exploring More Options: If you're looking for the best pre-workout supplements tailored to your unique needs, explore our wide collection of pre-workout supplements to find the perfect fit for your fitness goals.

Best Nootropic Pre-Workout Supplements: Shortlist

Wild Thing by Assault Labs – Top Choice: No. 1 Ranked Pre-Workout

Hosstility by Hosstile – Runner-Up

Wrecked Pre-Workout by Huge Supplements

Wrecked Enraged by Huge Supplements

Mother Bucker by Bucked Up

What are Nootropic pre-workouts?

A nootropic pre-workout is a type of dietary supplement designed to boost cognitive function and mental focus before engaging in physical exercise. Popularly called cognitive enhancers or "smart drugs", these supplements may improve various aspects of brain function, such as memory, alertness, creativity, and motivation.

Nootropic pre-workouts typically combine nootropic ingredients with traditional pre-workout ingredients like caffeine, creatine, and amino acids to provide a holistic approach to improving both physical and mental performance during exercise. The idea is to help individuals feel more mentally alert, focused, and energized, which can, in turn, lead to better workouts and potentially improved results.

Benefits of Nootropic Pre-workouts:

Enhanced Mental Focus: Nootropic pre-workouts are crafted to sharpen your mental acuity, helping you stay focused and in the zone throughout your workout, minimizing distractions and mental fatigue.

Improved Motivation: With the cognitive enhancers in these supplements, you'll experience increased motivation and a stronger drive to conquer your fitness goals. They help you stay determined and push through challenging workouts.

Physical Performance Optimization: Beyond mental benefits, these supplements often include ingredients to enhance physical performance. This can result in improved endurance, strength, and overall athletic performance.

Mind-Body Synergy: The unique combination of mental and physical benefits creates a synergy that leads to more productive workouts and a deeper mind-body connection.

5 Best Nootropic Pre-workouts

1- Wild Thing by Assault Labs

Wild Thing by Assault Labs

Introducing Wild Thing by Assault Labs – the ultimate, high-energy, focus, concentration, pump-pounding, muscle-and-mind-nourishing pre-workout. Packed with essential amino acids, creatine, and a range of nutrients designed to nourish your muscles as you train, this supplement goes the extra mile.

It boasts not one but two groundbreaking nootropics that take your focus and workout energy to unprecedented levels. Wild Thing sets a new standard for vascularity and pumps, surpassing any other pre-workout supplement and leaving you feeling incredibly pumped up. Transform your workouts down to the very last muscle fiber with the incredible power of Wild Thing by Assault Labs.

Key Benefits:

  • It improves your focus and concentration.
  • It supports mental cognition.
  • It increases your energy levels.
  • It boosts your muscle strength during a workout.
  • It enhances your muscle pump and endurance.
  • It helps improve your overall mood.
  • It promotes muscle recovery.
  • It decreases muscle fatigue and increases muscle control.

Key Ingredients:

Citrulline Malate: This non-essential amino acid is known to enhance muscular energy, improve performance in both anaerobic and aerobic activities, increase strength and power, boost nitric oxide production (resulting in muscle pumps), and alleviate post-training fatigue and soreness.

[Related] L-Citrulline vs Citrulline Malate: Which is the Better Nitric Oxide Booster?

Beta-Alanine (CarnoSyn®): This non-essential amino acid plays a vital role in elevating muscle carnosine levels, subsequently reducing muscle fatigue and enabling individuals to perform higher-intensity work.

Agmatine Sulfate (AgmaMax™): Derived from Arginine, this compound has garnered significant attention in the supplement industry. It's known for its capacity to stimulate growth hormone release and its role in enhancing Nitric Oxide production, leading to increased muscle pumps.

Creatine Hydrochloride: Research indicates that Creatine HCL has exceptional water solubility, which suggests the body can completely absorb it. This efficient absorption allows for faster regeneration of ATP (muscular energy), resulting in enhanced strength and muscle hydration.

L-Glutamine: This naturally occurring amino acid within your muscles, when taken as a supplement, supports muscle growth, prevents muscle breakdown, and accelerates muscle recovery.

Choline Bitartrate: converts into Acetylcholine, a neurotransmitter essential for numerous brain-body functions, including memory, cognitive processes, muscle control, and reflexes.

Caffeine Anhydrous: This pure and potent form of caffeine boosts high training intensity while also accelerating thermogenesis, promoting faster fat burning.

L-Tyrosine: This non-essential amino acid aids in preventing bodily fatigue, supports seamless brain function, enhances mood, and reduces anxiety.

L-Norvaline: L-Norvaline has demonstrated the ability to positively impact nitric oxide circulation, leading to increased nitric oxide production and improved nutrient delivery to muscles both during and after workouts.

Phenylethylamine Hydrochloride: Commonly referred to as PEA, this natural component supports cognitive enhancement, mood elevation, and heightened focus and stimulates the release of Acetylcholine, a crucial neurotransmitter involved in various brain-body functions.

N-Phenylacetyl-L-Prolylglycine Ethyl Ester (Noopept™): A potent component known for enhancing focus, concentration, learning ability, and memory recall speed while simultaneously reducing stress and anxiety levels. It is often combined with various choline forms, such as choline bitartrate, in supplement stacks.

Customer Reviews About the Product:


"Great! I can feel the preworkout unlike other brands.”

-Brett B.


“Excellent preworkout wakes you up fast keeps you alert and focused no crash, pump is amazing aswell.”


5-stars.pngWild thing indeed

“Best Pre-workout I have taken by far. I usually use total war by Redcon1 but this is definitely a better option in every way.”

-Tunde S.

5-stars.pngWild thing

“Enjoyed it, loved the tingle...good energy throughout the workout. Tastes great!”

-Ivan S.

5-stars.pngBest pre workout for older gym rats

“I've been using pre workout supps for many years, tried most top rated ones, and I always go back to wild thing. For an older guy that hits the gym, Wild Thing is just enough boost I'm looking for.”


2- Hosstility by Hosstile

Hosstility by Hosstile

Prepare to ignite your focus and concentration with Hosstile Supplements' leading product, Hosstility Pre Workout! Elevate your strength, endurance, muscle pumps, and energy levels, taking your workouts to unprecedented heights.

Hosstility is an all-in-one comprehensive Pre Workout formula with precisely measured ingredients designed to optimize your performance and deliver exceptional results. Featuring patented components and a transparent label, this high quality pre-workout also incorporates cognitive enhancers to maintain unwavering focus as you push your workouts to intense new extremes.

Key Benefits:

  • It improves your mental cognition.
  • It boosts your focus and concentration.
  • It increases your energy levels.
  • It boosts your muscle pumps.
  • It promotes muscle strength and endurance.

Key Ingredients:

Pure L-CITRULLINE: This pre-workout supplement provides a potent 6-gram dose of ultra-pure fermented L-citrulline. Once absorbed, it converts to L-arginine in the body, resulting in elevated levels of both L-arginine and nitric oxide.

[Related] L Citrulline Dosage for Pump and Performance: How Much Do You Need?

This boost leads to enhanced vasodilation, the expansion of blood vessels, facilitating improved blood flow, and the increased delivery of essential nutrients and oxygen to working muscles during your workout.

NO3-T arginine nitrate: It combines nitric acid with L-arginine to create an incredible pump-enhancing component. The combination of these two potent, scientifically supported ingredients has been demonstrated to elevate plasma nitric oxide levels more effectively than each on its own.

Research has also revealed enhanced N.O. bioavailability when L-arginine is paired with L-citrulline. In HOSSTILITY Pre Workout, we take L-citrulline to the next level by adding 2 grams of NO3-T Arginine Nitrate, facilitating intense, enduring, muscle-pumping effects.

PEAK02®: An organically certified blend of six adaptogenic mushrooms, these mushrooms enable your body to navigate and conquer both physical and mental stress, elevating performance, power output, and endurance.

Creatine Monohydrate: Hosstility's blend combines various creatine forms, such as creatine gluconate, creatine phosphate, creatine ethyl ester, creatine taurinate, and creatine anhydrous. Creatine is known for enhancing muscle volume, building muscle, and preventing muscle fatigue.

Betaine Anhydrous: An anabolic muscle-building compound demonstrated in studies to boost strength, power, and endurance and simultaneously alleviate muscle soreness.

Huperzine A: A nootropic that indirectly enhances acetylcholine levels by inhibiting its breakdown. Huperzine contributes to cognitive well-being, protecting the brain and supporting the generation of new brain cells.

Alpha GPC: It improves short-term memory, mental drive, learning, and attention.

TeaCrine: Chemically similar to caffeine but with long-lasting effects, it is widely known for its mood-enhancing benefits.

Infinergy: Comprising a caffeine and malic acid blend, this component not only helps prevent energy crashes but also mitigates potential stomach discomfort caused by caffeine.

Customer Reviews About the Product:

5-stars.pngAmazing pre

“Great pumps, great energy, great focus. Also take in the morning and have zero crash. Highly recommend”


5-stars.pngGreat Energy and Pump

“Hosstility is a well formulated pre workout that is one of the best stim pre workout products i've used for energy and pump. Even at half serving I got the energy I needed for my workout and my arms were pumped. Not to mention the taste profile on both the peach and watermelon are off the charts. Hosstile is known for their amazing taste and they knocked it out of the park with this pre workout. I would highly recommend giving it a try if you haven't.”

-Josh S.

3- Wrecked Pre-Workout by Huge Supplements

Wrecked Pre-Workout by Huge Supplements

Unleash Your Inner Beast: Huge Supplements is here to shatter your previous personal records with their latest pre-workout, "Wrecked." This powerhouse formula, consisting of 17 potent ingredients, promises to elevate your performance to astonishing levels.

Wrecked delivers a substantial 30-gram serving, igniting your energy levels, intensifying your focus, and producing extraordinary muscle pumps. Users have reported significant improvements in endurance, results, and overall physique.

Key Benefits:

  • It improves your focus and concentration.
  • It enhances your energy levels.
  • It boosts your muscle pumps and endurance.
  • It supports your workout intensity.
  • It increases your strength and power.

Key Ingredients:

L-Citrulline: Once absorbed, it converts into L-arginine in the body, resulting in increased L-arginine and nitric oxide levels. This boost results in increased vasodilation, dilating blood vessels, facilitating enhanced blood flow, and better delivery of oxygen and nutrients to working muscles during exercise.

Beta Alanine: As a non-essential amino acid, it plays a crucial role in elevating muscle carnosine levels, effectively reducing muscle fatigue and enabling individuals to perform more work at high-intensity levels.

[Related] Unlock the Benefits of Pre-Workout with Beta-Alanine

Betaine Anhydrous: A naturally occurring compound found in the body and certain foods like beets and seafood. It works by reducing homocysteine levels and by doing so, betaine anhydrous helps reduce the risk of heart disease and weakened bones.

Bodybuilders leverage this compound to enhance strength, size, and power. Additionally, Betaine impairs insulin levels, boosting protein synthesis to promote muscle growth.

S7: A blend of seven plant-based ingredients, S7 has been scientifically shown to increase nitric oxide levels by 230%. It works by increasing the body's nitric oxide production.

Theobromine: A naturally occurring compound known for its stimulating properties, capable of boosting energy levels, enhancing focus, and increasing motivation.

Agmatine Sulfate: The primary advantage of this ingredient is its ability to enhance blood flow to the muscles, resulting in heightened muscle pumps.

L-Tyrosine: This non-essential amino acid prevents your body from burning out while supporting smooth brain function, mood enhancement, and reducing anxiety.

HydroMax: It provides pumps by drawing water into muscle cells, giving you a full, swole appearance while also maintaining proper hydration.

Malic Acid: Demonstrated in studies to enhance exercise performance and increase muscle endurance.

Alpha GPC (L-Alpha glyceryl phosphorylcholine): It is a natural choline compound in the brain. Alpha GPC supplements swiftly transport choline across the blood-brain barrier, enhancing mood, and mental vitality, and stimulating the growth of new brain cells.

4- Wrecked Enraged by Huge Supplements

Wrecked Enraged by Huge Supplements

Introducing Wrecked Enraged by Huge Supplements: The best pre-workout formula crafted to propel your workouts to new heights. This potent combination incorporates scientifically proven ingredients to provide an extraordinary surge in energy, focus, and endurance, empowering you to conquer even your most intense training sessions.

Key Benefits:

  • It helps boost your mental focus and clarity.
  • It increases your energy level.
  • It helps enhance your power and stamina.
  • It improves your muscle pumps.
  • It helps speed up your muscle recovery.

Key Ingredients:

Beta Alanine: It is a naturally occurring non-essential amino acid that helps reduce the accumulation of lactic acid. By doing so, it allows you to keep performing at your best for longer during your workouts.

Alpha GPC is a cholinergic compound derived from soy lecithin. It's notable for its ability to enhance the production of acetylcholine, a neurotransmitter crucial for cognitive function, muscle control, and memory.

Additionally, it aids in the synthesis of phosphatidylcholine, a vital component of cell membranes. Studies have also suggested that Alpha GPC can play a protective role in reducing age-related cognitive decline.

[Related] Unlock Your Fitness Potential with Alpha GPC: A Game Changer in Health and Performance

Caffeine Anhydrous, Di-Caffeine Malate, and Caffeine Citrate:

Caffeine Anhydrous, the dehydrated caffeine form, allows precise dosing for accuracy. Di-caffeine malate combines caffeine with malic acid, offering a slower release of energy to minimize potential jitters. Caffeine Citrate, on the other hand, rapidly delivers an instant energy boost.

The synergy of these caffeine sources works together to provide a balanced and sustained energy release, reducing the risk of energy crashes during workouts.

Halostachine (50mg) is a natural alkaloid extracted from the Halostachys capsica plant. It shares structural similarities with ephedrine but offers fewer side effects and a shorter half-life. When consumed, it prompts an increase in heart rate and blood pressure, resulting in improved delivery of oxygen and nutrients to muscles. This, in turn, delivers a distinct surge in energy without the energy crashes and jitters often linked to other stimulants.

Huperzine A 1% (Huperzia serrata Leaf Extract) is sourced from the Chinese club moss plant, Huperzia serrata.It works as an acetylcholinesterase inhibitor, which means it prevents the breakdown of acetylcholine. Moreover, it also enhances memory, learning, and overall cognitive function.

Black Pepper Fruit Extract 95% (Piper nigrum): It contains the active compound piperine. This compound plays a crucial role in enhancing the bioavailability of other nutrients and supplements by inhibiting the enzymes responsible for their metabolism. Additionally, black pepper fruit extract exhibits antioxidant and anti-inflammatory properties, which can contribute significantly to overall health and well-being.

5- Mother Bucker by Bucked Up

Mother Bucker by Bucked Up

Mother Bucker sets itself apart with a completely transparent label, a range of mouthwatering flavors, multiple ingredients for impressive pumps, a hefty 400mg of caffeine, and a blend of focus and cognition enhancers.

What makes Mother Bucker truly exceptional is its inclusion of three clinically trademarked ingredients that maximize blood flow and pumps. It's time to push your limits and achieve what you never thought possible with Mother Bucker by Bucked Up!

Key Benefits:

  • It increases your muscle pumps.
  • It boosts your mental focus.
  • It supports cognition.
  • It improves your energy levels.
  • It provides more power.
  • It helps enhance endurance.
  • It promotes mind-muscle connection.
  • It increases dopamine.

Key Ingredients:

Beta Alanine: This non-essential amino acid elevates muscle carnosine levels, reducing muscle fatigue and enhancing high-intensity performance capacity.

L-Citrulline: Once absorbed, this component converts into L-arginine in the body, resulting in elevated L-arginine and nitric oxide levels. This boost leads to enhanced vasodilation, expanding blood vessels, and facilitating improved blood flow, along with a superior supply of nutrients and oxygen to working muscles during exercise.

Nitrosigine: This ingredient is a patented blend of bonded arginine silicate, meticulously designed to provide workout-related advantages. It has been scientifically proven for safety and efficacy in multiple studies.

The findings are clear, demonstrating that Nitrosigine increases Nitric Oxide (N.O.) production, leading to enhanced muscle pumps, improved blood flow, and heightened focus and energy during workouts.

[Related] Unlocking the Power of Nitrosigine: Our Top Picks for Supplements That Deliver

L-Tyrosine: This amino acid is crucial for concentration and drive. L-tyrosine is a precursor to neurotransmitters dopamine and norepinephrine, which are vital for cognitive function. Adding L-Tyrosine to your regimen enhances mental clarity, ensuring sustained focus even during the toughest workouts.

HydroPrime: Similar to glycerol but with enhanced pumps and minimal clumping.

Huperzine A: A plant-based alkaloid extract known for its ability to prevent acetylcholine breakdown. It can elevate acetylcholine levels for up to six hours after consumption. Huperzine A also contributes to hormonal balance, memory retention, support for mitochondria and liver health, and the prevention of neuron death.

Alpha GPC: A growth hormone enhancer that's been clinically proven to enhance mental focus, helping you stay in the zone during your workouts.

Astragin: Clinically proven to heighten Citrulline absorption, enabling optimal blood flow and amplified pumps during your workout.

Customer Reviews About the Product:


“Super excited about this one, formula looks good and the flavors too. Let's go!”


How to Choose the Best Nootropic Pre-Workout

Selecting the right nootropic pre-workout supplement can significantly impact your workout experience and overall fitness journey. Here are essential factors to consider when making your choice:

Ingredients and Transparency

Look for a product with a transparent label, listing all ingredients and their respective dosages. This transparency ensures you know exactly what you're consuming.

Nootropic Components

Assess the presence of nootropic ingredients, such as Alpha GPC or L-Tyrosine. These elements can boost mental focus, enhancing your cognitive performance during workouts.

Stimulants and Caffeine

Check the caffeine content and its sources. While caffeine can provide an energy boost, be mindful of the dosage to avoid excessive jitters or energy crashes.

Clinical Studies

Look for products with ingredients backed by clinical research for safety and effectiveness. Reliable studies can provide assurance of the supplement's benefits.

Personal Goals

Consider your fitness objectives. If you prioritize energy and focus, choose a pre-workout that emphasizes these aspects. If you're more concerned about muscle pumps, opt for one with ingredients tailored to that purpose.

Reviews and Recommendations

Read user reviews and seek recommendations from experienced athletes and fitness enthusiasts. Their feedback can give valuable insights into the effectiveness and overall experience of a product.

Tolerance and Sensitivity

Assess your tolerance to stimulants and nootropics. If you are sensitive to caffeine, you may want a milder option or choose a product that offers caffeine alternatives.

Flavor and Taste

Although not the most critical factor, the flavor and taste of the supplement can impact your overall experience. Find a flavor that you enjoy making it easier to incorporate into your routine.

Brand Reputation

Investigate the brand's reputation and reviews. Reliable brands with a history of quality products are a safer choice.


Keep an eye out for products that align with your budget. While price is a factor, it's essential to balance cost with ingredient quality and effectiveness

FAQs: Best Nootropic pre-workout supplements

Q: What benefits do nootropic pre-workouts offer?

A: Nootropic pre-workout supplements offer several benefits, including enhanced mental focus, improved motivation, and optimized physical performance. By promoting synergy between the mind and body, these supplements lead to more productive workouts and a deeper mind-body connection, ultimately improving overall fitness outcomes.

Q: What are the common ingredients in nootropic pre-workouts?

A: Common ingredients in nootropic pre-workouts include caffeine, L-citrulline, beta-alanine, and various nootropics like Alpha GPC, L-Tyrosine, and Huperzine A.

Q: Is it safe to use nootropic pre-workouts?

A: Nootropic pre-workout supplements are generally safe for healthy adults, but individual safety depends on specific health conditions. Caution is advised for individuals with heart disease, liver disease, or high blood pressure, as certain ingredients, such as caffeine or stimulants, may worsen these conditions. Additionally, interactions with medications can occur, affecting their effectiveness or causing adverse effects.

Q: When should I take a nootropic pre-workout supplement?

A: For the best results, aim to consume your nootropic pre-workout supplement approximately 30 minutes to an hour before you begin your workout.

Q: What are the potential side effects of nootropic pre-workout supplements?

A: Nootropic pre-workout supplements are generally safe when used as directed, but individual responses may vary. Common side effects can include mild jitters, increased heart rate, or an upset stomach, primarily due to ingredients like caffeine. However, these effects are often dose-dependent and temporary. If you experience persistent or severe side effects, it's advisable to discontinue use and consult a healthcare professional.

Final Thoughts

In conclusion, Nootropic pre-workout supplements can supercharge your workouts by boosting both your mind and body. From sharpened focus and increased motivation to improved physical strength and endurance, these innovative formulas can elevate your fitness journey to new heights.

So, whether you're a seasoned athlete looking for that extra edge or just starting your fitness quest, it's time to unlock your full potential – sharper in mind and stronger in body. Rewrite your fitness story and reach new heights in every workout. Your best self awaits.


  • Philip P, Sagaspe P, Taillard J, Mandon C, Constans J, Pourtau L, Pouchieu C, Angelino D, Mena P, Martini D, Del Rio D, Vauzour D. (2019 Dec 17) Acute Intake of a Grape and Blueberry Polyphenol-Rich Extract Ameliorates Cognitive Performance in Healthy Young Adults During a Sustained Cognitive Effort
  • Adam G Parker, Allyn Byars, Martin Purpura, and Ralf Jäger (2015 Sep 21) The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility
  • Michael J Glade and Kyl Smith (2015 Jun) Phosphatidylserine and the human brain

Written and Sponsored by Leonard Shemtob

Leonard Shemtob is President of Strong Supplements. Leonard has been in the supplement space for over 20 years, specializing in fitness supplements and nutrition. Leonard appears on many podcasts, written over 100 articles about supplements and has studied nutrition, supplementation and bodybuilding. 

Leonard's articles have been published in many top publications around the web. Leonard enjoys weight training, playing basketball and yoga, and also enjoys hiking. In his free time he studies and works on improving himself. For more detailed information, visit his official blog.

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