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Glycogen Supplement: How It Works, Benefits, and Best Options

Glycogen Supplement: How It Works, Benefits, and Best Options

Posted by Leonard Shemtob on Jul 22, 2025

Glycogen is your body’s main source of stored energy, especially during exercise. When you train hard or do long workouts, your glycogen levels can drop, making you feel tired and weak. That’s where glycogen supplements come in.

These supplements help refill your energy stores faster, support muscle recovery, and improve performance. In this article, we will explain what glycogen supplements are, how they benefit your health and fitness, and share some of the best options available today.


Quick Summary

  • Glycogen supplements help restore energy levels after intense exercise or long workouts.
  • They support muscle recovery and reduce fatigue by refilling the body’s glycogen stores.
  • Best used before, during, or after workouts for endurance and performance benefits.
  • Ideal for athletes, runners, and active individuals needing quick energy replenishment.
  • The article also lists the top glycogen supplement options to help you choose the right one.
  • Our top pick for the best glycogen supplement is GlycoPhase by SNS, which helps optimize carbohydrate use, enhance glycogen storage, and support better energy during workouts.

First, What Is Glycogen?

Glycogen is a form of stored carbohydrate that your body uses for energy. When you eat carbs like rice, bread, or fruit, your body breaks them down into glucose (sugar). Some of this glucose is used right away for energy, but the extra is stored in your liver and muscles as glycogen.

During physical activities like running, cycling, or even walking, your muscles rely on glycogen as their main source of energy. When glycogen stores run low, you may feel tired or weak. This is why maintaining healthy glycogen levels is important, especially for athletes or anyone who stays active regularly.

However, your body doesn't use all this glucose at once. Instead, it cleverly converts the excess glucose into glycogen for future use, primarily storing it in two key locations:

  1. Muscle Glycogen: Your muscles hold a significant amount of glycogen, which serves as their immediate energy reserve. When you exercise, especially during high-intensity or prolonged activities, your muscles tap into these glycogen stores to power contractions and sustain effort.
  2. Liver Glycogen: Your liver also stores glycogen. This liver glycogen plays a crucial role in maintaining stable blood glucose levels throughout your body. When blood sugar drops (for example, between meals or during fasting), the liver breaks down its glycogen stores and releases glucose into the bloodstream to fuel your brain and other organs.

Glycogen Structure

Glycogen is a complex carbohydrate or a polysaccharide, meaning it's formed from many smaller sugar units linked together. Specifically, it's composed of numerous glucose molecules connected by two main types of bonds:

  1. Alpha-1,4 Glycosidic Bonds: These are the primary links that connect glucose units in a straight chain, forming the "trunk" and main "branches" of our metaphorical tree. These chains can be quite long.
  2. Alpha-1,6 Glycosidic Bonds: These are the crucial "branch points." Every 8-12 glucose units along a chain, a new branch sprouts off, connected by an alpha-1,6 bond. This extensive branching is a defining feature of glycogen.

This branching pattern gives glycogen a tree-like, compact shape with layers of glucose chains radiating outward. These branches make glycogen more soluble and provide many endpoints, so enzymes can quickly add or remove glucose when the body needs energy.

Structurally, glycogen molecules are organized around a core protein called glycogenin, which acts as a primer for forming the initial glucose chains.

Because of its branched and compact nature, glycogen stores a large number of glucose molecules—often tens of thousands—in a small, dense particle. This design allows the body to rapidly access glucose to fuel muscle activity or maintain blood sugar levels whenever required.

Additionally, glycogen in the cells is stored in a hydrated form, bound with water, making it safe to store large amounts of glucose without causing harmful effects related to cell water balance.


How Glycogen Works

Glycogen functions as your body's on-demand carbohydrate fuel reservoir, constantly being built up (synthesized) and broken down (mobilized) based on your energy needs. The entire process revolves around glucose, your body's preferred immediate energy source.

Glycogenesis: Building Glycogen Stores

When you consume carbohydrates, your digestive system breaks them down into glucose. This glucose is then absorbed into your bloodstream.

If your body doesn't need all that glucose for immediate energy, it initiates a process called glycogenesis. During glycogenesis, individual glucose molecules are linked together to form longer, branched chains of glycogen.

This glycogen is primarily stored in:

  • Muscles: Muscle glycogen is reserved almost exclusively for the energy demands of those specific muscles during activity.
  • Liver: Liver glycogen acts as a central reservoir, helping to maintain stable blood sugar levels for the entire body, especially for the brain and other vital organs that rely heavily on glucose.

Glycogenolysis: Releasing Energy

When your body requires energy, particularly during exercise or periods between meals, it triggers the breakdown of glycogen through a process called glycogenolysis. Enzymes specifically designed for this task begin to cleave off individual glucose units from the branched glycogen molecule.

Here's how it plays out in different contexts:

  • During Exercise (Muscle Glycogen): As you run, lift weights, or engage in any intense physical activity, your muscles demand a rapid supply of energy. They quickly access their internal glycogen stores, breaking them down into glucose, which is then converted into ATP (adenosine triphosphate) – the direct energy currency of your cells. The higher the intensity and duration of your activity, the faster your muscle glycogen stores are depleted.
  • Between Meals/Fasting (Liver Glycogen): When you haven't eaten for a while and blood glucose levels start to drop, your liver steps in. It breaks down its stored glycogen and releases glucose directly into your bloodstream. This is vital to keep your brain functioning optimally and maintain overall energy balance throughout the day.

Benefits

  • Improved Endurance and Stamina: For activities like long-distance running, cycling, or team sports, a full tank of glycogen is essential. It allows your muscles to keep producing power and maintain a high level of effort throughout the entire duration of your activity.
  • Boost Energy: Glycogen is the body’s main fuel during physical activity. Supplements help refill your energy stores, so you can work out longer and feel less tired.
  • Improve Performance: With more glycogen available, your muscles can perform better, helping you run faster, lift heavier, or exercise harder.
  • Speed Up Recovery: After exercise, taking glycogen supplements helps your body restore energy more quickly, so you recover faster and feel ready sooner.
  • Delay Fatigue: By keeping your glycogen stores full, supplements can help delay the feeling of tiredness during long or intense workouts.
  • Support Muscle Health: Glycogen supports muscle function and strength, helping your muscles stay healthy over time.
  • Better Carb Use: Some glycogen supplements help your body use carbohydrates more efficiently, which can help with both energy and muscle growth.

Best Practices for Improving Glycogen Levels

Keeping your glycogen stores topped up is important for energy, performance, and fast recovery after exercise. Here are some simple tips and best practices:

  • Eat Enough Carbohydrates: Your main source of glycogen is the carbohydrates you eat. Make sure to include plenty of healthy sources like whole grains, fruits, vegetables, rice, and potatoes in your daily meals. The amount needed depends on your activity level, but athletes often benefit from 5–10g of carbs per kilogram of body weight per day.
  • Time Your Carbs Well: To quickly refill glycogen after exercise, eat carbs as soon as possible, ideally within 30–60 minutes. During this time, your muscles are best at absorbing glucose to restore glycogen.
  • Consider Carbohydrate and Protein Together: Combining carbs with a little protein (about a 4:1 ratio) after workouts can speed up muscle recovery and help refill glycogen even better.
  • Choose High-Quality Carbohydrates: Focus on nutrient-rich, low-glycemic index foods like wholemeal pasta, quinoa, sweet potatoes, and brown rice. These help keep blood sugar stable and are better for overall health.
  • Stay Well Hydrated: Glycogen binds to water in your body. If you’re dehydrated, it’s harder to store glycogen. Aim to drink 2.5–3.5L of water daily, especially around exercise.
  • Refuel During Long Workouts: For activities lasting longer than 60-90 minutes, consuming carbohydrates during exercise (e.g., sports drinks, energy gels, bananas) is crucial.
  • Adjust for Activity: On days with intense or long workouts, increase your carbohydrate intake to match the higher energy burn. For competitions or endurance events, carb loading (eating more carbs a few days before) can help maximize your glycogen reserves.
  • Replenish Immediately After Exercise: This is a critical window for glycogen resynthesis. Within 30-60 minutes after a hard workout, consume carbohydrates, ideally combined with some protein.
  • Avoid Too Many Refined Sugars: While sugary foods can quickly boost glycogen, relying on whole foods is healthier for your body in the long run.

What Are Glycogen Supplements?

Glycogen supplements are products designed to help increase or restore the body’s stores of glycogen, which is the main form of stored energy in muscles and the liver. Most glycogen supplements either contain fast-digesting carbs, ingredients that support better carb absorption, or compounds that improve how your body stores glucose as glycogen. Some may also include electrolytes, amino acids, or insulin-sensitivity boosters to further support performance and recovery.

Athletes and active individuals commonly use glycogen supplements to boost their energy levels, improve exercise performance, and speed up recovery after workouts. The supplements come in various forms, such as powders, drinks, gels, or bars, typically containing fast-digesting carbohydrates.

By providing easily accessible carbs, glycogen supplements support faster replenishment of glycogen stores that can be depleted during prolonged or intense physical activity. This replenishment helps delay fatigue, improve endurance, and enhance muscle recovery.


Benefits of Glycogen Supplements

  • Boosts Performance & Endurance: By rapidly topping up muscle glycogen, these supplements help you sustain high-intensity efforts longer, delay fatigue, and maintain peak power during workouts and events.
  • Accelerates Recovery: They quickly replenish depleted muscle glycogen after intense exercise, significantly speeding up recovery, reducing soreness, and preparing your muscles for the next session faster.
  • Prevents "Hitting the Wall": Strategic use can provide a steady glucose supply, helping endurance athletes avoid the severe fatigue and energy crashes that come from glycogen depletion.
  • Minimizes Digestive Issues: Unlike large meals, well-formulated glycogen supplements are designed for quick stomach emptying, reducing the risk of bloating or discomfort during activity.
  • Reduce Fatigue and Performance Drops: By keeping glycogen stores full, these supplements help delay the onset of tiredness, especially during long or high-intensity workouts.
  • Supports Muscle Growth: Adequate glycogen levels create an optimal environment for muscle protein synthesis, indirectly supporting muscle growth and repair alongside protein intake.
  • Improve How Your Body Uses Carbs: Some glycogen supplements include ingredients that enhance insulin sensitivity, helping your body store carbs more efficiently as glycogen.

Glycogen vs. Glucose vs. Glucagon

  • Glucose is a simple sugar and the main source of energy for your body’s cells. It comes from the food you eat, especially carbohydrates like bread, rice, and fruits. When glucose enters your bloodstream, your cells use it to produce energy.
  • Glycogen is a stored form of glucose. When you have more glucose than your body needs right away, it stores the extra glucose as glycogen, mainly in your liver and muscles. This stored energy can be quickly turned back into glucose when your body needs fuel, like during exercise or between meals.
  • Glucagon is a hormone made by the pancreas. Its job is to signal your liver to break down glycogen into glucose when your blood sugar is low, such as when you haven’t eaten for a while or during physical activity. This helps keep your blood sugar levels steady, ensuring your body and brain have the energy they need.

In short:

  • Glucose = energy source
  • Glycogen = stored form of glucose
  • Glucagon = hormone that unlocks glycogen when you need more glucose

Best Glycogen Supplements

GlycoPhase by SNS

1. GlycoPhase by SNS

GlycoPhase by Serious Nutrition Solutions (SNS) is a comprehensive glucose disposal agent (GDA) designed to improve insulin sensitivity and nutrient partitioning. It aims to optimize lean muscle growth and fat loss by enhancing glucose uptake into muscle cells while reducing fat storage.

Unlike some GDAs that primarily block carbohydrate absorption, GlycoPhase works to support efficient insulin utilization to maximize protein synthesis and carbohydrate use as muscle glycogen. The formula also targets sugar cravings, mood enhancement, and sustained energy, making it a multi-faceted product for metabolic health and athletic performance.

Key Ingredients:

  • Chromium nicotinate glycinate chelate (300 mcg): A chelated form of chromium that supports insulin receptor activity and improved glucose uptake.
  • Agmatine Sulfate (1,000 mg): Modulates nitric oxide and imidazoline receptors, which can enhance glucose transport into muscles.
  • Berberine HCl (500 mg): Activates AMPK, promoting insulin sensitivity and glucose disposal via GLUT‑4.
  • Bitter Melon Extract (10:1, 500 mg): Contains compounds (charantin, vicine, polypeptide‑P) that support blood sugar regulation and glycogen metabolism.
  • Banaba Leaf Extract (2% corosolic acid, 300 mg): Corosolic acid enhances insulin receptor activation and GLUT-4-mediated glucose uptake.
  • Gymnema Sylvestre Extract (25% gymnemic acids, 300 mg): May block sugar absorption in the gut and support better insulin signaling.
  • Alpha‑Lipoic Acid (150 mg) + Na‑R‑ALA (100 mg): These support antioxidant activity and improve insulin sensitivity and cellular glucose uptake; Na‑R‑ALA is a more bioavailable form.
  • Saffron (30 mg): May aid in blood sugar control and appetite regulation.
  • BioPerine® (10 mg): A black pepper extract (95% piperine) that enhances the absorption of other nutrients.

Key Benefits

  • Improves glucose disposal: Enhances insulin-mediated uptake of carbs into muscle while limiting fat storage.
  • Enhances insulin sensitivity: Synergy of chromium, berberine, and gymnema helps support better metabolic response.
  • Supports Fat Loss: By keeping glucose away from fat cells and reducing sugar cravings, GlycoPhase may indirectly assist in fat loss during high-carb diets or phases.
  • Muscle Performance and Recovery: Facilitates better glycogen storage and replenishment, lending to more productive training sessions and speedier recovery.
  • Stable Mood and Energy: Some users report improved mood and stable energy, potentially linked to more controlled blood sugar throughout the day.

SlinMax by Performax Labs

2. SlinMax by Performax Labs

SlinMax by Performax Labs functions as a nutrient partitioning supplement and advanced glucose disposal agent. It is formulated to leverage the anabolic effects of insulin, promoting muscle growth, improved vascularity, and fat loss while reducing the likelihood of carbohydrate-induced fat storage.

SlinMax is tailored for resistance-trained athletes and those using carbohydrate-rich diets, aiming to efficiently manage post-meal glucose and maximize nutrient delivery to muscle tissues.

Key Ingredients:

  • Gymnema Sylvestre Extract (std. 25% Gymnemic Acids): May blunt intestinal glucose absorption and assist insulin signaling.
  • Berberine HCl: Influences gut health and blood sugar, primarily by activating AMPK and improving insulin sensitivity.
  • Banaba Extract (min. 2% Corosolic Acid): Known for insulin-mimicking properties and potential to enhance glucose transport to muscle cells.
  • Isolyn™ (Sodium R-Alpha Lipoic Acid, Na-R-ALA): A highly bioavailable form of alpha-lipoic acid, supporting insulin sensitivity and nutrient delivery.
  • Cinnamon Bark Extract (Cinnamomum Cassia): Recognized for its blood glucose-lowering effects and possible support of glycemic control.
  • Chromium (as Chromium Picolinate): An Essential mineral that enhances the action of insulin in glucose metabolism.
  • BioPerine® (Black Pepper Extract, std. to 95% Piperine): Used for improving the absorption and efficacy of other active ingredients.

Key Benefits

  • Optimizes Carbohydrate Utilization: SlinMax is structured to promote efficient glucose uptake into muscles, reducing the likelihood of carbs being stored as body fat.
  • Supports Anabolic Environment: By mimicking and enhancing insulin action, SlinMax fosters an environment favorable for muscle growth and nutrient uptake post-meal.
  • Improved Blood Sugar Regulation: Ingredients such as berberine, banaba, and cinnamon extract help buffer blood sugar spikes and support stable energy, which is critical during periods of high-carb intake.
  • Promotes lean muscle benefits: Helps with fuller muscles and potentially better pumps and recovery.
  • May support fat loss: By optimizing carb use and reducing fat storage, it could help with body composition goals.
  • Enhanced Ingredient Absorption: BioPerine® ensures that active ingredients are absorbed more efficiently, maximizing their metabolic impact.

Customer Reviews: SlinMax

MR

“Slin Max is one of few products is working with Insulin.

How result after 4 weeks is volume of muscle increase, also cover carb deficit and added 4 Kg muscle.

Feel pump and drive by maximum.

I use Slin Max with Brown Nutrition Sleep and Grow, that is make my workout great.

Both of products are natural and get a pleasure.

Please, add them in stock.”

-Dainis


Glycolog by Blackstone Labs

3. Glycolog by Blackstone Labs

Glycolog by Blackstone Labs is an insulin mimetic and nutrient partitioning agent designed to optimize carbohydrate metabolism and support lean muscle gains. It works by enhancing insulin sensitivity and maximizing insulin utilization, helping the body shuttle glucose and amino acids directly into muscles instead of fat cells.

This process supports glycogen storage in muscle tissue, improves glucose metabolism, and can contribute to fat loss by minimizing excess carbohydrate storage as fat.

Key Ingredients:

  • Chromium (as chromium polynicotinate, 300 mcg): Regulates blood sugar by enhancing insulin sensitivity and reducing sugar cravings, helping cells absorb glucose more efficiently.
  • Gymnema Leaf Extract (25% gymnemic acids, 10:1, 1000 mg): Helps lower blood sugar levels by increasing insulin production and sensitivity, supporting enhanced glucose uptake in muscles.
  • Bitter Melon (500 mg): Promotes glucose uptake into skeletal muscles, reduces glucose storage in the liver, and may reduce fat accumulation by lowering blood sugar.
  • Super Berberine (300 mg): A bioavailable form of berberine that activates AMPK, improving insulin sensitivity and glucose absorption by muscle cells.
  • Cinnamon Bark Extract (~30% polyphenols, 25:1, 250 mg): Acts as an insulin mimetic, slows carbohydrate digestion to increase insulin response, and supports glucose transport into muscle tissue.
  • Sodium R-Lipoate (150 mg): A potent antioxidant that supports carbohydrate metabolism, lowers blood sugar, and promotes insulin sensitivity.
  • BioPerine® (5 mg): Enhances absorption and bioavailability of active ingredients, increasing the formula’s effectiveness.

Key Benefits:

  • Maximizes Insulin Utilization: Improves how your body uses insulin to drive nutrients into muscles rather than fat cells.
  • Increases Insulin Sensitivity: Enhances cellular response to insulin, allowing better glucose uptake and storage as muscle glycogen.
  • Supports Lean Muscle Growth: Encourages nutrient partitioning that promotes muscle gains over fat accumulation.
  • Improved nutrient partitioning: Helps redirect carbohydrates into muscle rather than fat tissue.
  • Improves Glucose Metabolism: Supports balanced blood sugar levels and efficient energy use from carbohydrates.
  • Enhances Fat Loss: By directing carbohydrates away from fat storage, it contributes to leaner body composition.
  • Stimulates Glycogen Storage: Boosts glycogen replenishment in muscles for improved energy and recovery.
  • Enhanced Muscle Fullness & Pumps: By promoting greater glucose and glycogen storage in muscles, it can contribute to increased muscle volume and a more "full" appearance, often referred to as muscle pumps.

Customer Reviews: Glycolog

5 Star Rating Customer Review My helper

“I have difficulties with weight gain. Glycologist +Epi-Cat + ****** from Blackstone labs helped to increase weight by 2 kg in 6 weeks . Helps to digest a large amount of carbohydrates. Improved the work of the stomach. I recommend for the recovery of the pancreas. Good price on this site.”

-VASILIY

 

5 Star Rating Customer Review Killer product

“I ran this bad boy for 16 weeks. It was great pre workout. It helped keep me lean while I bulked. I felt like I had more energy,my muscles looked fuller and I gained 6 pounds of muscle. Will use again!!!!!”

-steve

 

 Do not compare to insulin but it works

“You still need to watch your diet. It is not about eating all carb you want, but it does help. If you train properly and eat well, you will see a little bit of a difference.”

-Jesus


Huge Supplements Utilize

4. Huge Supplements Utilize

Utilize by Huge Supplements is a glucose disposal agent (GDA) formulated to optimize carbohydrate metabolism and improve insulin sensitivity. The multi-ingredient blend is designed to channel nutrients into muscle cells, support steady blood sugar, and enhance metabolic flexibility.

This supplement is intended to minimize fat storage from carbohydrate intake while maximizing its anabolic effects, making it suitable for individuals on high-carb diets or those looking to optimize their post-workout recovery and muscle-building processes.

Key Ingredients:

  • Vitamin D3 (as Cholecalciferol) (50 mcg): Beyond its role in bone health, Vitamin D3 has been linked to insulin sensitivity and glucose metabolism, potentially improving the body's response to insulin.
  • Chromium (from Chromium Picolinate) (63 mcg): An essential trace mineral that enhances the action of insulin. It is believed to help insulin bind to its receptors, improving glucose uptake by cells and supporting healthy blood sugar levels.
  • Berberine HCL (1500 mg): A powerful plant alkaloid widely studied for its ability to activate AMPK (AMP-activated protein kinase), a key enzyme involved in energy metabolism. It helps improve insulin sensitivity, reduce glucose production in the liver, and enhance glucose uptake by muscle cells.
  • Bitter Melon (Momordica charantia)(fruit) (500 mg): Traditionally used to support blood sugar levels. It contains compounds that may act like insulin, helping glucose enter cells, and inhibit the absorption of sugar in the gut.
  • Gymnema Sylvestre (leaves) (300 mg): An herb known for its "sugar-destroying" properties. It may help reduce sugar cravings, block sugar absorption in the intestines, and stimulate insulin secretion from the pancreas.
  • Alpha Lipoic Acid (ALA) (200 mg): A potent antioxidant that acts as an insulin mimetic, meaning it can mimic the effects of insulin. ALA can enhance glucose uptake into muscle cells and improve insulin sensitivity.
  • Cinnamon Bark Extract (Cinnamon Ceylon) 20:1 (125 mg): Research suggests that cinnamon can improve insulin sensitivity and glucose metabolism, potentially by acting on insulin receptors and regulating glucose transport. Ceylon cinnamon is often preferred for its lower coumarin content compared to Cassia cinnamon.
  • Banaba Leaves Extract (Lagerstroemia speciosa) (std. 1% Corosolic Acid) (100 mg): Contains corosolic acid, which is believed to enhance glucose transport from the bloodstream into cells and improve insulin signaling, contributing to blood sugar regulation.

Key Benefits:

  • Optimized Nutrient Partitioning: Effectively directs carbohydrates and amino acids into muscle tissue for energy and growth, minimizing storage as body fat.
  • Enhanced Insulin Sensitivity: Significantly improves the body's response to insulin, leading to more efficient glucose uptake by muscle cells.
  • Supports Blood Sugar Control: A comprehensive blend of ingredients works synergistically to help maintain stable and healthy blood sugar levels, reducing spikes and crashes.
  • Promotes Muscle Glycogen Storage: Facilitates superior glycogen replenishment in muscles, providing a readily available energy source for intense workouts and contributing to muscle fullness.
  • Improved Muscle Fueling: Supports robust glycogen replenishment and sustained energy delivery to muscles, which is critical for maximizing performance during workouts and accelerating post-exercise recovery.

Insuload by Hi-Tech Pharmaceuticals

5. Insuload by Hi-Tech Pharmaceuticals

Insuload by Hi-Tech Pharmaceuticals is a glucose disposal agent (GDA) designed to optimize carbohydrate utilization and enhance muscle growth and recovery. It functions as an insulin mimetic, aiming to shuttle glucose and amino acids more effectively into muscle tissue rather than promoting fat storage.

The supplement is formulated with a transparent ingredient label and uses Hi-Tech's proprietary Cyclosome Delivery technology, which is intended to improve the bioavailability of its ingredients by allowing them to bypass initial breakdown in the liver and digestive tract.

Key Ingredients:

  • Gymnema Sylvestre Extract 75% Gymnemic Acids (166.667mg): Supports blood sugar balance, enhances insulin production, and can help reduce sugar cravings.
  • Phellodendron Amurense Extract 97% Berberine HCl (100mg): Known to lower blood glucose levels and aid in cellular glucose absorption.
  • R-Alpha Lipoic Acid Sodium Salt (83.333mg): A powerful antioxidant that supports carbohydrate metabolism and enhances insulin sensitivity.
  • Bitter Melon Extract 20% Charantin (166.667mg): Promotes glucose uptake in muscle cells and may help reduce fat formation.
  • Green Coffee Extract 50% Chlorogenic Acids (166.667mg): Contains compounds that can help regulate blood sugar levels.
  • Cinnamon Bark Extract 20:1 (83.333mg): Acts as an insulin mimetic, potentially improving insulin sensitivity and glucose transport.
  • Banaba Leaf Extract 2% Corosolic Acid (83.333mg): Aids in glucose uptake into cells.
  • Trigonella Foenum-Graecum Extract (Containing 4-Hydroxyleucine) (83.333mg): May improve glucose metabolism.
  • Chromium (As Chromium Polynicotinate) (120mcg): An essential trace mineral that assists insulin function and blood sugar regulation.

Key Benefits:

  • Optimizes Muscle Glycogen: Enhances the body's ability to store carbohydrates as glycogen in muscle cells, crucial for energy and performance.
  • Improves Nutrient Partitioning: Directs carbohydrates and amino acids primarily to muscle tissue for growth and repair, rather than fat storage.
  • Efficient glycogen and amino shuttling: Insuload’s insulin-mimicking ingredients promote quicker delivery of carbs and protein into muscles, reducing catabolism.
  • Enhances Recovery and Growth: By facilitating faster shuttling of amino acids and glycogen to muscles, it supports post-workout recovery and overall muscle development.
  • Increases Carbohydrate Utilization: Helps the body more effectively use consumed carbohydrates, reducing their potential for conversion to fat.
  • Superior Bioavailability: Utilizes Cyclosome Delivery technology to increase the absorption and effectiveness of its active ingredients.

Lean GLP by SNS

6. Lean GLP by SNS

Lean GLP is a stimulant-free supplement formulated to support weight management by enhancing GLP-1/GIP activity, improving metabolic efficiency, and curbing appetite. This dietary supplement employs a multi-phase, science-backed blend of nine active ingredients, each targeting a different pathway—appetite regulation, thermogenesis, blood sugar control, and nutrient partitioning.

Key Ingredients:

  • Saberry® (Emblica Officinalis) Extract (1000 mg): Standardized to beta-glucogallin 10%, this extract from Indian gooseberry (Amla) is known for its antioxidant properties and potential to support healthy blood sugar levels and metabolic function.
  • Dihydromyricetin (DHM) (500 mg): A natural flavonoid that may improve insulin sensitivity and support liver health; it also has antioxidant effects and may assist in reducing inflammation.
  • DNF-10® Satiety Peptides (500 mg): Derived from Saccharomyces cerevisiae, these peptides are aimed at promoting feelings of fullness (satiety), which can help regulate appetite and support weight management.
  • Momordicin® (Momordica charantia extract) (500 mg): Bitter melon extract standardized for bitter principles and charantin, traditionally used to support blood sugar regulation by enhancing glucose uptake and mimicking insulin effects.
  • Eriomin® (Lemon Fruit extract) (200 mg): Standardized to 70% eriocitrin, this citrus flavonoid blend may improve glycemic control, reduce inflammation, and support overall metabolic health.
  • GlucoVantage® (Dihydroberberine) (100 mg): A bioavailable form of berberine that improves insulin sensitivity and glucose metabolism by activating AMPK, aiding in better blood sugar regulation.
  • CaloriBurn GP® (Grains of Paradise Seed Extract) (75 mg): Contains 12.5% 6-Paradol, this thermogenic ingredient may support increased metabolism and fat oxidation, assisting with body composition.
  • Curcousin® (Standardized to 99% Calebin-A) (50 mg): A form of turmeric extract that provides anti-inflammatory and antioxidant benefits, supporting metabolic health and potentially aiding insulin sensitivity.
  • Bioperine® (Black Pepper Fruit Extract) (10 mg): Enhances the absorption and bioavailability of other ingredients, making the overall formula more effective.

Key Benefits:

  • Appetite control via GLP‑1 modulation: Saberry®, Eriomin®, Momordicin®, and DNF‑10® help reduce hunger and cravings.
  • Fat burning and thermogenesis: CaloriBurn GP® and Curcousin® activate brown fat and promote fat oxidation.
  • Enhanced Insulin Sensitivity: Formulated with multiple ingredients designed to make the body more responsive to insulin, promoting efficient glucose uptake by muscle and liver cells.
  • Improved Glycogen Storage: Indirectly supports muscle glycogen replenishment through better insulin regulation.
  • Stable blood sugar and metabolic efficiency: GlucoVantage®, DHM, and bitter melon support insulin sensitivity and glucose control.
  • Stimulant-free metabolic support: Provides energy and fat loss assistance without caffeine or stimulants—suitable for sensitive individuals.
  • Multi-pathway synergy for body composition: Targets appetite, fat use, blood sugar, and metabolic health in a coordinated approach.

GAINS CANDY™ GlucoVantage® - Insulin Mimicker for Fat Loss & Muscle Building by Alpha Lion

7. GAINS CANDY™ GlucoVantage® by Alpha Lion

GAINS CANDY™ GlucoVantage® by Alpha Lion is a glucose disposal agent (GDA) and insulin mimicker specifically formulated to improve carbohydrate utilization while supporting fat loss and muscle building. Its key active ingredient, Dihydroberberine (DHB), is a highly bioavailable derivative of berberine that enhances insulin sensitivity and glucose metabolism more efficiently than traditional berberine.

This allows carbohydrates to be preferentially stored as muscle glycogen and used for energy instead of being converted to fat. The supplement targets fat cell growth inhibition and promotes the conversion of fat stores into energy, making it suitable for individuals aiming to enjoy carbohydrate-rich meals without compromising fat loss goals.

Key Ingredients:

  • GlucoVantage® (Dihydroberberine, DHB) (100 mg): A potent insulin sensitizer with 5x greater bioavailability than berberine, it promotes improved carbohydrate tolerance, healthy insulin response, and glucose metabolism. It also inhibits fat cell (adipocyte) growth and supports fat oxidation.

Key Benefits:

  • Optimizes Carbohydrate Tolerance: Enhances the body’s ability to handle carbohydrates efficiently, directing them towards muscle glycogen rather than fat storage.
  • Increases Insulin Sensitivity: Improves cellular response to insulin, facilitating better nutrient uptake and blood sugar regulation.
  • Supports Healthy Blood Glucose Levels: Helps maintain balanced glucose metabolism to prevent spikes and crashes.
  • Promotes Fat Loss: Facilitates the conversion of fat stores into energy and inhibits the growth of fat cells.
  • Aids Muscle Building: Increases nutrient delivery to muscles, supporting glycogen replenishment and anabolic processes.
  • May Assist Anti-Aging Processes: Related metabolic improvements and fat loss mechanisms can contribute to long-term metabolic health.

Customer Reviews: GAINS CANDY™ GlucoVantage

5 Star Rating Customer Review Amazing

“Great GDA that helps with carbs”

-Jordan J.

 

5 Star Rating Customer Review This supplement helps aid your insulin receptiveness

“I have stacked this Gains Candy Glucovantage with Gains candy mitoburn and Gains Candy Caloriburn, and I must say, it’s nice to be able to not feel groggy after a late night cheat meal, especially when your in a pinch and need to eat quick! I wake up feeling refreshed and hungry, ready to go, and there’s no doubt it’s because of the insulin aiding abilities of Glucovantage. Where I’d normally feel bloated and tired after a not so great meal on the go, this totally helps aid in the digestion process of those unwanted carbs! 10/10 recommend.”

-Daniel


Final Thoughts

Glycogen is the body’s stored fuel, especially for muscles during activity. It helps maintain energy, strength, and workout performance. Supplements in this category aim to support storage, usage, and recovery.

Some focus on nutrient partitioning, while others enhance insulin sensitivity or carb uptake. Each formula works differently, depending on its ingredients and purpose. This article explored how glycogen functions, its benefits, and the best products designed for support.

Written and Sponsored by Leonard Shemtob

Leonard Shemtob is President of Strong Supplements and a published author. Leonard has been in the supplement space for over 20 years, specializing in fitness supplements and nutrition. Leonard appears on many podcasts, written over 100 articles about supplements and has studied nutrition, supplementation and bodybuilding. 

Leonard's articles have been published in many top publications around the web. Leonard enjoys weight training, playing basketball and yoga, and also enjoys hiking. In his free time he studies and works on improving himself. For more detailed information, visit his official blog.

FAQs: Glycogen Supplement

A: Glycogen is the storage form of glucose. It's stored in your muscles and liver and is used for quick energy during exercise or when your blood sugar drops.
A: When your muscle glycogen stores are low, you may feel tired, weak, and unable to perform well during workouts or physical activity.

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A: No, glycogen stores are limited and deplete after extended or intense activity. The body stores roughly 100 grams in the liver and 400 grams in muscle tissue, which typically lasts for about 24 hours, depending on activity and diet.
A: Eating a balanced diet rich in complex carbohydrates, timing carb intake around workouts, staying hydrated, and getting regular exercise can help maintain and replenish glycogen stores effectively.
A: Indirectly, yes. Some glycogen-focused supplements improve insulin sensitivity and nutrient partitioning, which may help your body use carbs better and reduce fat storage.

A: Glycogen supplements are most effective when used strategically:

  • Before exercise: To top off muscle glycogen for peak performance.
  • During long/intense workouts: To provide sustained energy and prevent depletion.
  • Immediately after exercise: To rapidly replenish muscle glycogen stores and kickstart recovery.
A: Yes—strategically. Use them only around workouts ("targeted keto") to fuel performance without disrupting ketosis long-term. Consult a healthcare professional if unsure.