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​Top 5 Non-Methylated Prohormones for Building Muscle and Strength

​Top 5 Non-Methylated Prohormones for Building Muscle and Strength

Posted by Leonard Shemtob on Aug 16, 2023

Top 5 Non-Methylated Prohormones for Building Muscle and Strength

Are you looking to build muscle and strength without the risks associated with methylated compounds? You're entering a realm of safe and remarkable transformation. Non-methylated prohormone is a type of prohormone that does not contain a methyl group. This makes them less likely to be broken down by the liver and, therefore, less harmful to liver health.

In this article, we unveil the top 5 non-methylated prohormones that can supercharge your muscle gains and boost your strength, helping you achieve the results you've been working hard for.

Whether you're just starting out on your fitness quest or you've been at it for years, this guide is your invaluable resource for achieving remarkable results. Get ready to redefine your fitness experience and watch your goals come to life with these powerful prohormones.

[Related Article] 5 Best Prohormones for Cutting

Short Summary

Safe Muscle Gains: Discover the power of non-methylated prohormone, potent supplements that enhance muscle gains and strength without the health risks associated with methylated versions.

Tailored Fitness: Whether you're an athlete aiming for peak performance, a fitness novice taking your first steps, or an experienced individual seeking progress, this guide caters to your specific fitness goals and background.

Expert Insights: Explore a selection of five carefully chosen non-methylated prohormones, unlocking the science behind their muscle-building potential while prioritizing your safety. Begin your transformative journey toward a stronger, more powerful physique today.

Take the First Step: Embark on your muscle-building journey with our top recommended prohormone, Super Mandro by Hard Rock Supplements.

Discover More: Explore a comprehensive range of prohormones tailored to meet your unique and personal fitness needs, helping you achieve your muscle and strength goals effectively.

What is Prohormone?

Prohormones are hormone precursors that your body converts into active hormones. Bodybuilders and athletes use them to get stronger muscles and better performance. When you take a prohormone, it turns into anabolic hormones in your body.

Today, the term 'prohormones' doesn't only refer to precursors of hormones but also includes compounds that are active on their own.

Similar to anabolics, prohormones are strong androgen receptor agonist that helps increase natural testosterone levels. 

The prohormones available today are different from those available before the 2015, because they have a better delivery system and absorption rate, which means they are less taxing on the liver.


  • It increases lean muscle mass
  • It improves muscle strength and power
  • It speeds up muscle recovery
  • It helps improve body recomposition
  • It increases pumps and vascularity

What is a Non-Methylated Prohormone?

A non-methylated prohormone is a prohormone that does not have a methyl group attached to it. Non-methylated prohormone supplements support muscle gains and strength without using a process called methylation.

Methylation involves adding a chemical group called a methyl group to the prohormone compound. Non-methylated prohormones are designed to have fewer potential risks and side effects compared to their methylated prohormones.


  • It is generally considered safer than methylated prohormones.
  • It is less likely to damage the liver.
  • It increases lean muscle mass and strength.
  • It accelerates post-workout recovery.
  • It improves athletic performance.
  • It may help maintain a healthier hormonal balance.
  • It might contribute to fat loss and improved body composition.

5 Best Non-Methylated Prohormones

1- Super Mandro by Hard Rock Supplements

Super Mandro by Hard Rock Supplements

Super Mandro is a bulking agent that helps you gain lean muscle mass. It is more powerful than testosterone and works faster than other products. It helps you improve lean muscle mass and increase muscle hardness. It is a tried-and-true formula that has been shown to help people gain 8.8 lbs of muscle in 30 days.

Typically, compounds like 1-Androsterone require high doses to work well, as the body often breaks down much of the compound after ingestion.

However, Hard Rock Supplements has improved the formula using the Liposomal Stealth Delivery System. This technology protects the compound as it moves through your body, ensuring minimal breakdown until it's ready to take action.

Key Benefits:

  • It increases your lean muscle mass.
  • It is 7 times more anabolic than testosterone.
  • It promotes increased strength.
  • It enhances muscle hardness.
  • It improves muscle definition.
  • It boosts your muscle pumps.
  • It supports fat loss.
  • It helps increase protein synthesis.

Key Ingredient:

1-Andro (3-beta-hydroxy-5-alpha-androst-1-en-17-one): Derived from DHEA, this ingredient undergoes a dual conversion process, becoming a compound that's 7 times more anabolic than testosterone. Notably, it doesn't convert to estrogen, preventing water retention.

Liposomal Stealth Technology: Normally, compounds like 1-Andro lose around 86% of their effectiveness as they enter the bloodstream due to breakdown by the liver. But with Liposomal Technology, its absorption increases up to 99%, increasing the compound's potency by up to 6x.

Previously, taking 100mg of 1-Andro resulted in around 14mg absorbed, whereas now you could absorb up to 99mg from the same dose!

Customer Reviews About the Product


“I've been using this one for 3 years and it has never disappointed me.”

-Antonio M.

5-stars.pngGreat product and timely shipping

“I purchased Supermandro and have gained 8 pounds. This is awesome for me being I cannot gain weight without help from supplements. This product works and no bad side effects. Will continue to purchase during bulk phase.”

-Beau B.

5-stars.pngGreat product/ no side effects

“As a 55 year old weight training enthusiast I love the bump in strength and muscle hardness I get when using Super Mandro, which I do on average Every few months. I also appreciate the drop in body fat percentage!”

-Paul H.

5-stars.pngSuper mandro

“It's great. Gotten bigger quick... I would recommended to anybodys the super mandro.”

-Gabriel G.

5-stars.pngMandro is legit

“The first time I bought this product was after reading the Texas A&M study where participants gained 8lbs of muscle and lost 2lbs of fat in a month. When I used it I gained 20mg a but some of it was fat. Still amazing results. This will be my second time and I’m hoping for similar results as the study!”


2- Andro the Giant by Hard Rock Supplements

Andro the Giant by Hard Rock Supplements

Step into the world of the Giant Lifestyle with the backing of Hard Rock Supplements' muscle-building breakthrough – Andro the Giant!

Andro the Giant is a new mass-building supplement from Hard Rock Supplements. It is loaded with 4-Androsterone, an anabolic bulking agent that converts into testosterone, increasing natural testosterone production. This means that Andro the Giant can help you gain muscle mass and strength.

4-Androstero is an anabolic agent that converts into testosterone through a two-step conversion process.

Key Benefits:

  • It increases your muscle strength and energy.
  • It helps increase muscle mass.
  • It speeds up muscle recovery.
  • It boosts protein synthesis.
  • It helps block muscle-wasting hormones.
  • It boosts libido.
  • It reduces your body fat.
  • It improves muscle pumps.
  • It enhances your overall mood.

Key Ingredients:

4-Androsterone - Also known as 4-DHEA, this compound is derived from DHEA and converted into testosterone. Testosterone is both anabolic and androgenic, which means it can help you gain muscle mass as well as strength.

It can also increase your red blood cell count, improving your muscle pumps and protein synthesis. 4-Androsterone is a true bulking compound, which can help you gain a lot of mass. However, it can also cause some water retention.

It is also possible for 4-Androsterone to convert to estrogen, so it is a good idea to combine it with an estrogen blocker.

[Related] The Best Estrogen Blocker for Bodybuilding 2023

Likewise, this supplement also utilized Liposomal Stealth Technology. This technology helps to increase the absorption of 4-Andro by 99%. This means 6 times more of the compound is absorbed into the bloodstream. For example, if you take 100 mg of 4-Andro without Liposomal Stealth Technology, only 14 mg will be absorbed. But with Liposomal Stealth Technology, 99 mg will be absorbed.

Customer Reviews About the Product

5-stars.pngAndro is a Giant

“After two weeks of ramping up the dosing you can feel the pop on bench,deadlifts and squats. Getting to the midpoint of cycle and expect base strength to increase by 15% by time cycle is over. Strong product, I highly recommend!”

-Christopher O.

5-stars.pngMy go to supplemet.

“Andro the Giant is by far the best 4 andro supplement. Great as a test base.”


5-stars.pngStuff works

“Great expierence like everything else. Takes about a week to adjust. But will definitely tell a difference and feel great”

-Christopher M.

5-stars.pnggood product

“i stacked this with Super Mandro and put on @ 8 lbs in 30 days. strength went up as well. will be using again. good stuff”

-Brad M.

5-stars.pngBEAST MODE!!

“4 andro test base for your stacks or for your bulk , as always strong supplements brings the good stuff !! Research or ask as strong supplements have an amazing costumer service with advice !!!”


3- Androvar™ by Hard Rock Supplements

Androvar™ by Hard Rock Supplements

Hard Rock Supplements proudly presents Androvar™ - Your Ultimate Anabolic Solution, delivering More muscle, More strength, and a More comprehensive cycle experience! It contains Epiandrosterone, which converts into Stanolone, a compound that is 10 times stronger and more androgenic than testosterone. This means you can expect leaner, drier, and harder gains.

But that's not all – Androvar™ goes beyond. Unlike other products, Androvar provides you with the proper dosage (300mg – 400 mg daily ) for a full 6 weeks.

Epiandrosterone doesn't convert to estrogen; instead, it aids in reducing estrogen levels, melting stubborn body fat, and eliminating unwanted water weight. It can even assist in lowering gyno. Plus, it boosts muscle density, supercharges strength, and fits into various cycles, offering more options for your fitness goals.

For those engaged in anabolic cycles, Androvar™ is your ideal stacker, elevating gains and fat loss while maintaining high energy levels and libido.

Key Benefits:

  • It helps increase lean muscle mass.
  • It increases muscle hardness and strength.
  • It improves your vascularity and muscle pumps.
  • It boosts libido.
  • It enhances your muscle definition.
  • It helps lose excess fat.
  • It helps reduce water retention.
  • It enhances the intensity of your workout.
  • It increases protein synthesis.
  • It helps improve a sense of well-being.

Key Ingredients:

Epiandrosterone is a derivative of DHEA, which is a hormone that is produced naturally in the body. It can also be found in pine pollen. Epiandrosterone is a precursor to Stanolone, which is also known as Dihydrotestosterone (DHT). DHT is a potent androgenic hormone responsible for muscle gains, strength, and sex drive.

[Related] Top 5 Epi Andro Supplements For Fitness and Bodybuilding

Low levels of DHT can lead to a decreased sex drive and can also compromise the muscle-building process. Proper and high levels of DHT can promote improved muscle strength and mass, better overall mood, boost libido, and decreases body fat and water retention.

Customer Reviews About the Product

5-stars.pngGreat Product.

“Hands down one of the best if not the best epiandro supplements I have ever used in a long time. Beast Mode!!!”


5-stars.pngAwesome Product

“Best supplement I ever used”

-John C.

5-stars.pngGood to go

“In search for a mild but efficient product, Androvar is really satisfactory. I didn't stack it up. I did a good diet but not hard cutting and the effect starts to show 2 weeks after the start. I keep good sleep and have good training session. I recommend it as a starter.”


5-stars.pngGreat Product!

“I've been ordering products from strong supplement shop for a couple years and this is my favorite go to bulking supp.”


5-stars.pngThe best add-on for a stack.

“This product takes the PH market to new levels. I've been using this for the last 2 cycles and it literally makes your muscle definition skyrocket. When stacked with Mandro the Giant, the results are evident within 1.5 weeks. It acts as an amplifier for the 1 and 4 andro. I've done used this product for the last year and the results are staggering. What a great product.”


4- Ultimate R-Andro by Hard Rock Supplements

Ultimate R-Andro by Hard Rock Supplements

Introducing Ultimate R-Andro by Hard Rock Supplements – the cutting supplement that stands above the rest. Hard Rock Supplements took the original proven R-Andro Shred formula and, after extensive research and development, created Ultimate R-Andro, making it more powerful and more effective.

This advanced blend combines three potent ingredients – Androsterone, 7-KETO, and Arachidonic Acid.

Arachidonic Acid was clinically studied at the University of Tampa and has been shown to increase lean body mass, power, and strength. 7-KETO DHEA, the second ingredient, was also clinically studied and showed significant weight loss when compared to diet and exercise alone. And rounding out the trio is Androsterone, a muscle-hardening, strength-boosting, and vascular powerhouse.

This perfect trilogy of these three ingredients in one bottle propels Ultimate R-Andro to a whole new level.

Key Benefits:

  • It increases lean muscle mass and muscle hardness.
  • It helps improve strength and vascularity.
  • It reduces body fat.
  • It helps promote muscle gains.
  • It reduces water retention.
  • It helps improve overall mood.
  • It improves endurance and overall exercise performance.

Key Ingredients:

7-Keto DHEA: It activates enzymes that are responsible for fatty acid and carbohydrate metabolism. As we age, the body's production of 7-Keto DHEA declines. This can lead to a decline in metabolic rate. Clinical studies have shown that 7-Keto DHEA can help reverse this trend and improve metabolism and body mass index.

Androsterone: It helps increase muscle hardness, strength, and vascularity. It also improves fat loss by promoting lipolysis and converting TSH to T4. Moreover, it decreases estrogen-related effects like gyno, water retention, and female fat distribution.

This compound is similar to Epiandrosterone, but studies state that it is more potent androgen than Epiandrosterone.

Arachidonic Acid is an essential fatty acid promoting muscle gains and repair.

[Related] Arachidonic Acid, Fitness, and Supplementation

Customer Reviews About the Product

5-stars.pngUltimate r andro

“I went from 228 to 205 in 3 months with diet and intensity in the gym. While doing that i increased muscle hardness. Muacles popping out. Veins popping.. i actually increased strength. My energy and intensity is through the roof. This is the best supplement i have ever taken by far. I will always be using it spring summer time. No supplement has ever came close to the effects and results i got from this.”

-Matthew B.


“Wow! Major recovery time speed up. Lean hard muscle and strength gains. This is a solid supplement.”

-Lucas r.


“Just started this product and noticed right away strength was up, helps with leaning out after one week and energy level has increased. Hoping to put on size the next few weeks. So far , highly recommend!”


5-stars.pngGetting Ultimate!!

“This product easily increased my strength as I was able to set a PR on my deadlifts. Because of the enhanced recovery and endurance, I was able to work out daily despite working a full time job as well. As a natty product, you can’t go wrong with this one. I believe in the product so much I bought two more bottles. This product is worth it!”


5-stars.pngIt delivers!!

“I finished my bottle of this a few weeks ago. This run was nothing short of incredible!! The visible results in the mirror from day 1 to day 30 were highly noticeable! Energy, endurance, recovery, strength, size, libido. It was all there! I will, without a doubt, be running this again! Almost a little reminiscent of the good ol days of the "supplements" of the 90's...”


5- AbNORmaL by Blackstone Labs

AbNORmaL by Blackstone Labs

Introducing AbNORmaL by Blackstone Labs, the ultimate muscle-building powerhouse! This pure bulker is here to help you achieve remarkable muscle mass and strength gains with unparalleled anabolic potency!

AbNORmaL contains a compound that is 6x more anabolic than testosterone, so you can expect notable gains in muscle size and strength.

Key Benefits:

  • It helps increase lean muscle gains.
  • It enhances strength and power.
  • It increases your appetite.
  • It helps improve muscle recovery.
  • It increases protein synthesis.

Key Ingredients:

Norandrostenediol is a DHEA derivative that converts into Nandrolone or Nortestosterone in the body. It's similar to testosterone, but it's 6-12x more anabolic and has few side effects because it doesn't convert to estrogen or DHT. This means that both men and women can use it. Norandrostenediol helps you build muscle mass in a slow and consistent way.

Customer Reviews About the Product


“I increased 15kilo mass plus water in just 5 6 weeks top product”


5-stars.pngnot to shabby

“I took this for 60 days, 2 bottles. Did not disappoint. Put on a few pounds of muscle, not wet and sloppy. Pretty good quality muscle. took a little to see results so try to be patient lol”


Non-Methylated Prohormones: Frequently Asked Questions (FAQs)

Q: What are prohormones?

A: Prohormones are compounds that the body converts into active hormones, often used by bodybuilders and athletes to enhance muscle gains and performance.

Q: What are non-methylated prohormones?

A: Non-methylated prohormones are supplements that support muscle gains and strength without the use of methyl groups.

Q: What is the difference between methylated and non-methylated prohormones?

A: The main difference between methylated and non-methylated prohormones is the presence of a methyl group. Methylated prohormones have a methyl group, and on-methylated prohormones do not have a methyl group, making them less likely to cause liver toxicity.

Q: What are the benefits of using a non-methylated prohormone?

A: Non-methylated prohormone is generally considered safer for liver health, offers lean muscle mass gains, improves strength and power, accelerates post-workout recovery, enhance athletic performance, and may contribute to fat loss and improved body composition.


In conclusion, non-methylated prohormones offer a safe and effective route to achieving remarkable muscle gains and enhanced strength. These supplements minimize liver damage and potential health risks while providing benefits such as lean muscle mass gains, improved recovery, and enhanced athletic performance.

Whether you are a beginner or a seasoned fitness enthusiast, non-methylated prohormones offer a promising pathway toward achieving your muscle and strength goals.


Written and Sponsored by Leonard Shemtob

Leonard Shemtob is President of Strong Supplements. Leonard has been in the supplement space for over 20 years, specializing in fitness supplements and nutrition. Leonard appears on many podcasts, written over 100 articles about supplements and has studied nutrition, supplementation and bodybuilding. 

Leonard's articles have been published in many top publications around the web. Leonard enjoys weight training, playing basketball and yoga, and also enjoys hiking. In his free time he studies and works on improving himself. For more detailed information, visit his official blog.

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